More on familial and hereditary risk for prostate cancer

Slowly but surely we are learning more about the roles of family history and familial genetics (heredity) in determining risk for prostate cancer — and most especially risk for clinically significant forms of prostate cancer. … READ MORE …

A potential future for prostate cancer risk assessment

A recent article in the International Journal of Cancer lays out a possible future scenario for prostate cancer risk assessment that takes specific account of familial and hereditary risks for clinically significant prostate cancer. … READ MORE …

Why we get cancer: genetics, lifestyle, and just sheer chance

It has long been understood that many cancers occur as a consequence of errors in the replication of the genetic materials of cells (usually DNA) during the normal process of cell growth and replication. … READ MORE …

Parental diagnosis and familial risk for prostate cancer: an 78-year analysis

A new study in the European Journal of Cancer has confirmed the key importance of heredity (i.e., genetic inheritance) as one of the risks for prostate cancer and two other common forms of cancer (breast and colorectal cancers). … READ MORE …

CNV analysis hints at hereditary susceptibilities for prostate cancer

An new article on line in the Proceedings of the National Academy of Sciences or PNAS has further extended our understanding of the genetic and inheritable factors that may predispose individual patients to higher risk for clinically significant and aggressive forms of prostate cancer … READ MORE …

An update on hereditary and familial prostate cancers

For those interested in “brushing up” on their understanding of the risks associated with hereditary and familial forms of prostate cancer, we recommend a brief article in the April issue of the AUA News, which summarizes a “state of the art” lecture to be given by the author at the upcoming annual meeting of the American Urological Association. … READ MORE …

Prostate cancer news report: Thursday, May 14, 2009

News reports today cover such issues as:

  • Vitamin D and its possible role in development of prostate cancer
  • Genetic testing among hereditary prostate cancer families
  • Sex hormone levels and cognitive function in older men … READ MORE …

Link between heredity and prostate cancer survival times in Sweden

So it appears that prostate cancer survival (and not just risk for prostate cancer) runs in families — at least in Sweden!

There have been multiple studies designed to look at risk for prostate cancer based on familial history. And while family history is a known risk factor for prostate cancer, its effect on survival has not been clear at all. However, a study just published in the Journal of Clinical Oncology seems to show that “good and poor survival [times] in prostate cancer aggregate in families.” In other words (just as an example), if a father has prostate cancer and his cancer progresses quickly, then if his sons also get prostate cancer they are also at risk for a more aggressive form of the disease! The authors suggest that, in fact, factors governing survival in prostate cancer may be different from those governing risk for prostate cancer. This is certainly a novel concept. … MORE