After failure of first-line radiation, both kinds of salvage brachytherapy are equally effective

A group of researchers at Memorial Sloan-Kettering Cancer Center (MSKCC) reported in 2014 (see this link) on the outcomes of 42 patients with radio-recurrent prostate cancer treated with salvage high-dose-rate brachytherapy (sHDR-BT). The results were quite good — … READ MORE …

Is there an optimal treatment schedule for high-dose-rate brachytherapy?

Protocols for high-dose-rate brachytherapy (HDR-BT) monotherapy vary. In recent years, practitioners have adopted various schedules for patient and physician convenience. … READ MORE …

HDRBT monotherapy in treatment of high-risk prostate cancer

Three randomized clinical trials (Sathya et al., 2005; Hoskin et al., 2012; and Guix et al., 2013) established the combination of external beam radiation therapy (EBRT) with a high dose rate brachytherapy (HDRBT) boost as a standard of care in the treatment of high-risk prostate cancer. … READ MORE …

Initial study of single-dose HDR brachytherapy for localized prostate cancer

In the past, high-dose-rate (HDR) brachytherapy has been used alone or (more commonly) in combination with external beam radiation therapy (EBRT) for the treatment of localized prostate cancer. However, when used alone, it has been necessary to treat the patient with several sessions of HDR brachytherapy. … READ MORE …

More on the value of HDR brachytherapy added to EBRT

A few days ago we reported on a study which concluded that the addition of high-dose-rate (HDR) brachytherapy to intensity-modulated radiation therapy (IMRT) had limited short-term clinical benefit in the treatment of localized prostate cancer compared to IMRT alone. Newly published Australian data is arguably supportive of this viewpoint. … READ MORE …

IMRT alone vs. HDR brachytherapy + IMRT — short-term outcomes are similar

There have been strong suggestions over the years (at least from some physician groups) that the combination of brachytherapy with external beam radiotherapy (EBRT) was associated with superior outcomes compared to the use of EBRT alone in treatment of localized prostate cancer. … READ MORE …