High-dose EBRT, very high-dose EBRT, or brachy boost therapy – which is best for intermediate- and high-risk patients?

At last week’s Genitourinary Cancers Symposium, Amini et al. presented the results of a data analysis that addresses the question of which kind of high-dose radiation therapy has the best cancer control rates … READ MORE …

10-year outcomes after high-dose IMRT for localized prostate cancer

A new report from Memorial Sloan-Kettering Cancer Center has documented patient outcomes at 10 years after high-dose, intensity-modulated radiation therapy (IMRT)  for men initially diagnosed with clinically localized prostate cancer. … READ MORE …

Adverse toxicities of high-dose PBRT: a Phase II clinical trial

ACR 03-12 is a Phase II clinical trial designed by the American College of Radiology to test the safety and efficacy of 82 GyE (Gray equivalent) delivered using conformal proton beam radiation therapy (PBRT) for the treatment of localized prostate cancer. … READ MORE …

High-dose bicalutamide as second-line hormone therapy in CRPC patients

Historically there have been few really compelling data available to support the use of an additional or alternative antiandrogen as a second-line agent to extend either progression-free or overall survival of castration-resistant prostate cancer (CRPC) patients who progress after first-line hormone therapy (whether they have been treated by orchiectomy or medical castration with an LHRH agonist). … READ MORE …