Outcomes, survival, and HRQOL in trials of new drugs (and what they mean in practice)

A new paper in the journal Quality of Life Research has raised the question of whether it is possible to use available quality of life data from Phase III trials of new drugs in the treatment of advanced prostate cancer to make rational decisions about the use of those drugs in clinical practice. … READ MORE …

Patients’ sexual orientation and communication with healthcare providers

The ability and willingness of physicians to discuss issues related to sex, sexual function, and specific sexual activities with their patients (and their partners) before or after prostate cancer treatment is notoriously not seen to be high by most prostate cancer patients (although there are exceptions to that general rule). … READ MORE …

Prostate cancer treatment outcomes among gay men

A poster presentation given on Sunday at the AUA annual meeting (and an associated media briefing) strongly suggested that gay males diagnosed with prostate cancer tend to have less good clinical outcomes than straight males. … READ MORE …

Surgery, brachytherapy, HRQOL, and the SPIRIT trial

The Surgical Prostatectomy versus Interstitial Radiation Intervention Trial or SPIRIT was a Phase III, partially randomized clinical trial, conducted in the U.S.A. and Canada, and designed to compare radical prostatectomy (RP) and brachytherapy (BT) as first-line treatments for men with localized prostate cancer. … READ MORE …

Diabetes and quality of life among men with prostate cancer

It has long been recognized that the combination of prostate cancer and diabetes tends to have a notable impact on the health-related quality of life (HRQoL) of male patients. … READ MORE …

Quality of life after first-line treatment: a prospective, comparative study

Data to be published in the May 2010 issue of the Journal of Urology are going to make a lot of urologists rather less than happy about the implications for the use of radical prostatectomy as first-line treatment for prostate cancer. … READ MORE …

Prostate cancer news reports: Wednesday, January 13, 2010

Today’s news reports summarize papers recently published on:

  • Optimism, pessimism, and long-term health outcomes
  • External beam radiation + hormone therapy for high-risk patients
  • Quality of life and health utility after radical prostatectomy
  • Paclitaxel + estradiol combination therapy in men progressing after docetaxel-based chemotherapy … READ MORE …