Posted on June 21, 2018 by Sitemaster
We first reported data from the results of the RTOG 0938 trial in January 2016 when they were presented at the Genitourinary Cancers Symposium in that year. These results have now been formally published, and there are some changes to the data on publication, so Allen Edel has provided an update. … READ MORE …
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: body, hypofractionated, radiation, SBRT, stereotactic, toxicity | Leave a comment »
Posted on December 6, 2016 by Sitemaster
In several randomized clinical trials of external beam treatment of primary prostate cancer, we have seen that moderately hypofractionated intensity-modulated radiation therapy (HypoIMRT), accomplished in 12 to 26 treatments or fractions, is no worse than conventionally fractionated IMRT treatment (in 40 to 44 fractions). … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: hypofractionated, IMRT, life, quality, radiation, SBRT, stereotactic | 3 Comments »
Posted on September 29, 2016 by Sitemaster
There has been some question as to whether the toxicity of delivering very high doses of external beam radiation per treatment (or fraction) in fewer fractions (called “extreme hypofractionation” or SBRT) would be high compared to conventional dose rates per fraction. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Risk, Treatment | Tagged: 3D-CRT, extreme, hypofractionated, outcome, radiation, SBRT, stereotactic | Leave a comment »
Posted on January 9, 2016 by Sitemaster
Data reported at the recent Genitourinary Cancers Symposium have shown that the toxicities associated with stereotactic body radiation therapy (SBRT) are acceptable and similar whether the radiation is give as 5 or 12 doses. … READ MORE …
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: hypofractionated, radiation, SBRT, stereotactic, toxicity | 2 Comments »
Posted on October 1, 2015 by Sitemaster
The largest-yet randomized clinical trial comparing hypofractionated (fewer treatments or fractions) to normally fractionated intensity-modulated radiation therapy (IMRT) has proved that oncological outcomes and late-term toxicities were the same for both treatment schedules. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: hypofractionated, IMRT, outcome, radiation, therapy, trial | 15 Comments »
Posted on July 10, 2015 by Sitemaster
In a previous article, we looked at the experimental use of extreme hypofractionated radiation therapy (SBRT or SABR) to treat high-risk patients. Here, we take a closer look at an early (Phase I/II) safety study by Bauman et al. that shows why radiation safety is more complicated than just setting the treatment dose. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: hypofractionated, radiation, SABR, safety, SBRT | 1 Comment »
Posted on October 10, 2013 by Sitemaster
Many readers may be interested in reading an editorial just published in the Journal of Clinical Oncology that deals with “hypofractionation” (giving fewer doses of radiation therapy at higher dose levels) in treatment of localized prostate cancer. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: conventional, hypofractionated, IMRT, radiation | Leave a comment »
Posted on December 14, 2012 by Sitemaster
Advocates for proton beam radiation therapy (PBRT) are not going to be enamored of the article in the Wall Street Journal (WSJ) on the cost/benefit ratio of this form of treatment for localized prostate cancer. …
Filed under: Living with Prostate Cancer, Management, Treatment, Uncategorized | Tagged: benefit, cost, hypofractionated, PBRT, proton, radiation | 7 Comments »
Posted on September 27, 2011 by Sitemaster
A report to be presented at the upcoming meeting of the American Society for Radiation Oncology (ASTRO) offers 5-year outcome data from a trial comparing conventional intensity-modulated radiation therapy (IMRT) to the more recently developed hypofractionated IMRT for men with localized prostate cancer. … READ MORE …
Filed under: Management, Treatment, Uncategorized | Tagged: comparison, conventional, hypofractionated, IMRT, intensity-modulated radiation therapy, outcome | 1 Comment »
Posted on November 5, 2009 by Sitemaster
Two new studies reported at the American Society for Radiation Oncology (ASTRO) annual meeting yesterday discuss the potential of shorter courses of “hypofractionated” radiation therapy in the treatment of localized prostate cancer. … READ MORE …
Filed under: Management, Treatment | Tagged: hypofractionated, outcome, radiation, risk | 1 Comment »
Posted on June 13, 2009 by Sitemaster
Today’s news reports include information on:
- Outcomes comparing two types of radiation therapy
- Outcomes of younger vs. older men after radical prostatectomy
- The activity and safety of AZD0530 in CRPC … READ MORE …
Filed under: Drugs in development, Management, Treatment | Tagged: AZD0530, conformal beam, hypofractionated, old, radiotherapy, raduical prostatectomy, standard, young | Leave a comment »
Posted on June 12, 2009 by Sitemaster
Todays news reports adddress:
- Surgeon and hospital volume and outcomes to radical prostatectomy
- Adverse events associated with the use of hypofractionated, dose-escalated, IMRT
- Quality of sexual function after external beam radiation therapy
- Percentage of positive biopsy cores and response to first-line hormone therapy … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment, Uncategorized | Tagged: biopsy, core, EBRT, external beam radiation therapy, hormone therapy, hospital, hypofractionated, IMRT, radical prostatectomy, sexual function, surgeon, volume | Leave a comment »
Posted on June 9, 2009 by Sitemaster
Today’s news reports deal with items on:
- The mechanism of action of D,L-sulforaphane
- Isolation of an active protein from the bitter melon plant
- The potential of focal therapy for localized prostate cancer
- Reconstruction of the lower urinary tract after radical prostatectomy
- Hypofractionated intensity-modulated arc radiotherapy in N1 prostate cancer … READ MORE …
Filed under: Drugs in development, Management, Prevention, Treatment | Tagged: arc, bitter melon, focal therapy, hypofractionated, intensity-modulated, radiotherapy, reconstruction, sulforaphane, urinary tract | Leave a comment »
Posted on January 27, 2009 by Sitemaster
Today’s news deals with such items as:
- Toxicities associated with hypofractionated, intensity-modulated radiation therapy
- Incidental prostate cancer in male patients undergoing radical cystoprostatectomy for treatment of bladder cancer
- A Spanish review of photodynamic therapy
- A proposed mechanism of action for the investigational drug Apoptone™ (HE3235) … READ MORE …
Filed under: Diagnosis, Drugs in development, Management, Risk, Treatment, Uncategorized | Tagged: Apoptone, cystoprostatectomy, HE3235, hypofractionated, IMRT, photodynamic therapy | Leave a comment »