A possible future test to differentiate between risk for aggressive and indolent forms of prostate cancer

A new paper by an  international group of researchers from several different centers has maybe identified a new way to differentiate accurately between indolent and aggressive forms of prostate cancer at time of initial diagnosis. … READ MORE …

New terminology, IDLE threats, and human behavior (about cancer)

An article by Esserman et al. in the May issue of Lancet Oncology has again laid out the argument being made by a number of leading cancer specialists that “new terminology” is a necessary requirement for smarter discussions between all relevant parties about “indolent and precancerous disorders”. … READ MORE …

Active surveillance — a comprehensive review (with comment)

In another article in European Urology, Dall’Era et al. have provided a thorough review of published outcome data from the seven largest known series of patients being managed under active surveillance (AS). Unfortunately the full text of this article is not available on line. … READ MORE …

Why Ki-67 may not be USEFUL in predicting aggressive prostate cancer

A paper to be presented on Sunday at the upcoming annual meeting of the American Association for Cancer Research suggests that “the proliferative index as assessed by Ki-67 immunoreactivity is an independent predictor of aggressive prostate cancer.” … READ MORE …

Genetic variant “associated” with aggressive as compared to indolent forms of prostate cancer

Another new article in the Proceedings of the National Academy of Sciences has suggested the possibility of major progress in the prostate cancer research field — but at least this time the media seem to have got the story right! … READ MORE …

Cell cycle regulation and aggressive forms of prostate cancer

A new paper by Wang et al. in a recent issue of Cancer Research has proposed details of a specific connection between control over the growth and division of prostate cancer cells and clinical occurrence of the more aggressive forms of prostate cancer. … READ MORE …

All the prostate cancer news for Friday, August 8

Today’s news items all focus on issues that are closely connected to the recent and controversial  guidelines issued by the US Preventive Services Task Force:

  • The accuracy of current methods for predicting the likelihood of clinically insignificant (indolent) prostate cancer
  • The management of patients found to have incidental prostate cancer on treatment for benign prostatic hyperplasia (BPH), and
  • The risks of overtreatment of men in their 70s and 80s after a diagnosis of prostate cancer … READ MORE …