Adverse events of primary, intensity-modulated radiation therapy (IMRT)

In a recent commentary, the Sitemaster mentioned some common adverse effects of radical prostatectomy, some of which (e.g., perceived penile shrinkage, climacturia) are seldom mentioned by urologists to prospective patients, and are not routinely included in standardized quality-of-life questionnaires. … READ MORE …

PBRT vs. IMRT — patients can now enroll at more sites

The “New” Prostate Cancer InfoLink has consistently encouraged newly diagnosed patients who are thinking about radiation therapy as treatment for low- and intermediate-risk, localized prostate cancer to consider enrolling in the ongoing, randomized, Phase III clinical trial known as the PARTIQoL trial. … READ MORE …

The theoretical tissue-sparing effects of PBRT on non-cancerous tissues

Proponents of proton beam radiation therapy (PBRT) have long touted its theoretical, healthy, tissue-sparing effects. However, … READ MORE …

Risk for GU side effects higher after SBRT than after IMRT?

A recent, retrospective analysis of Medicare data suggests that men who have first-line stereotactic body radiation therapy (SBRT) are at somewhat higher risk for genitourinary (GU) side effects than men who select intensity-moduated radiation therapy (IMRT). … READ MORE …

Image guidance technology and radiation therapy for localized prostate cancer

Prostate cancer patients who are to be treated with any type of intensity-modulated radiation therapy (IMRT) for localized prostate cancer today can be pardoned if they are confused by the many ways in which that radiation therapy can be aimed and targeted through the use of image guidance (IGRT) systems. The variety of methods is significant and growing. … READ MORE …

Acute and mid-term side effects of high-dose, image-guided IMRT in first-line treatment of localized prostate cancer

Two recent papers have reported data relevant to the application of high-dose, image-guided, intensity-modulated forms of radiation therapy (IGRT/IMRT) in the first-line treatment of men with localized prostate cancer. … READ MORE …

Toxic side effects of adjuvant, salvage IMRT post-surgery

Prostate cancer patients are commonly concerned about the potential risks for side effects associated with adjuvant and salvage radiation therapy after a preceding, first-line, radical prostatectomy. … READ MORE …

Other prostate cancer news: Wednesday, December 8, 2010

Other prostate cancer news out today includes:

  • An article in the Wall Street Journal about the financial motives behind intensity-modulated radiation therapy (IMRT)
  • Approval from the FDA for a Phase III pivotal trial of PROSTVAC-VF … READ MORE …

Slightly fewer (severe) complications after IMRT compared to CRT

According to a media release from the University of Pennsylvania Health System, (and another from the American Society of Radiation Oncology [ASTRO]), intensity-modulated radiation therapy (IMRT) is associated with fewer complications than traditional, three-dimensional conformal radiation therapy (3D-CRT) in the treatment of non-metastatic prostate cancer. … READ MORE …

Proton beam vs. intensity-modulated RT: out on the battle lines

The relative merits of proton beam radiotherapy (PBRT) and the more commonly available intensity-modulated radiotherapy (IMRT) as forms of external beam radiation for prostate cancer are much debated … with minimal supportive evidence on either side of the debate because no comparative trial has ever been carried out. … READ MORE …

Prostate cancer news reports: Tuesday, June 9, 2009

Today’s news reports deal with items on:

  • The mechanism of action of D,L-sulforaphane
  • Isolation of an active protein from the bitter melon plant
  • The potential of focal therapy for localized prostate cancer
  • Reconstruction of the lower urinary tract after radical prostatectomy
  • Hypofractionated intensity-modulated arc radiotherapy in  N1 prostate cancer … READ MORE …