The results of a small, randomized, double-blind, placebo-controlled trial to evaluate the role of curcumin in prostate cancer patients already treated on intermittent androgen deprivation therapy (IADT) have recently been published. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: adbrogen, curcumin, deprivation, duration, IADT, intermittent, recurrence, tim | 8 Comments »
The other day we mentioned two articles in a recent issue of JAMA Oncology that dealt with the role of intermittent androgen deprivation therapy (IADT) in the management of progressive prostate cancer today. We have now had the good fortune to be able to read both of the two articles in full, thanks to a kind correspondent. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: androgen, continuous, deprivation, IADT, intermittent | 6 Comments »
One of the small number of major prostate cancer presentations at the ASCO meeting this year comes from the so-called PRINCE trial of intermittent chemotherapy in men with castration-resistant prostate cancer (CRPC). … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: chemotherapy, continuous, docetaxel, intermittent, outcome | 5 Comments »
The debate over the relative values of continuous (CADT) and intermittent (IADT) forms of androgen deprivation therapy (ADT) in the treatment of advanced forms of prostate cancer has now been ongoing for years. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, CADT, continuous, deprivation, IADT, intermittent | 8 Comments »
The results of early, large, randomized trials of intermittent (IADT) vs. continuous androgen deprivation therapy (CADT) have provided conflicting results. However, one of the flaws in early trials was the failure to ensure that men enrolled into these trials all actually had an optimal initial response to androgen deprivation (ADT). … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, continuous, deprivation, intermittent, outcome | 4 Comments »
So the initial results of the AVIAS trial are not going to make a couple of our regular readers too happy — although at least a trial of the type they have been asking for has now been carried out. … READ MORE …
Filed under: Drugs in development, Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen deprivation, dutasteride, IADT, IADT3, intermittent | 34 Comments »
A new paper in Clinical Genitourinary Cancer provides some intriguing information about determining the likelihood of good and less good long-term responses to intermittent androgen deprivation therapy (ADT) among men with non-metastatic prostate cancer. Be warned: This is going to be a long post with a lot of data. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, intermittent, Management, outcome, prognosis | 8 Comments »
A poster at the Genitourinary Cancers Symposium yesterday will bring joy to Chuck Maack’s heart. It addressed the use of dutasteride in the off-therapy cycles of intermittent androgen deprivation therapy (ADT). … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, deprivation, dutasteride, intermittent | 4 Comments »
About 18 months ago, at the 2011 Genitourinary Cancer symposium in Orlando, Florida, Klotz et al. presented data from a large trial of intermittent (IADT) versus continuous androgen deprivation therapy (CADT) in the management of men with progressive prostate cancer after prior treatment with first- or second-line radiation therapy. We reported their data at the time. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, CADT, continuous, deprivation, IADT, intermittent, therapy | 5 Comments »
New data from the randomized FinnProstate Study VII trial comparing outcomes of men randomized to treatment with either intermittent (IAD) or continuous (CAD) androgen deprivation therapy are going to further confuse physicians and patients about the relative merits of these two types of androgen deprivation therapy. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, CAD, continuous, deprivation, IAD, intermittent | 7 Comments »
THE "NEW" PROSTATE CANCER INFOLINK 