SBRT vs. moderate hypofractionation: same or better quality of life?

In several randomized clinical trials of external beam treatment of primary prostate cancer, we have seen that moderately hypofractionated intensity-modulated radiation therapy (HypoIMRT), accomplished in 12 to 26 treatments or fractions, is no worse than conventionally fractionated IMRT treatment (in 40 to 44 fractions). … READ MORE …

Outcomes, survival, and HRQOL in trials of new drugs (and what they mean in practice)

A new paper in the journal Quality of Life Research has raised the question of whether it is possible to use available quality of life data from Phase III trials of new drugs in the treatment of advanced prostate cancer to make rational decisions about the use of those drugs in clinical practice. … READ MORE …

Can a man be too young for active surveillance?

There is a “conventional wisdom” that active surveillance (AS) is only for older men, and that younger men are better off having immediate radical treatment, typically prostatectomy (RP).

Longer life or quality of life? What do newly diagnosed patients really want?

A third, and interesting, late-breaking poster to be presented at the upcoming annual meeting of the American Urological Association looked into patient perspectives on quality of life as opposed to quantity of life in prostate cancer treatment decision making. … READ MORE …

Clinician characteristics affect likelihood of PSA testing in older men

A new article in JAMA Internal Medicine has quantified (to some extent) how characteristics of clinicians affect the probability of older men being given PSA tests within the Veterans Administration health system here in the US. … READ MORE …

A duty of care in the management of prostate cancer

A new article in the journal Nature Reviews: Urology is entitled, “The implications of ageing and life expectancy in prostate cancer treatment.” It’s an important issue. … READ MORE …

A Lancet Oncology editorial

This week’s issue of The Lancet Oncology carries an interesting editorial entitled “Perceptions of cancer in society must change.” It’s well worth a read. And the full text is available on line. … READ MORE …