A group of Spanish clinical researchers have reported recent data from a small study designed to address an unanswered question about the recovery of (relatively) normal hormonal function after completion of androgen deprivation therapy (ADT). … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, deprivation, function, hormone, long-term | 4 Comments »
After > 50 years of use of various forms of androgen deprivation therapy (ADT), we still don’t really have a clear idea of whether or the degree to which long-term, continuous ADT can affect cognitive function — although there is no doubt at all that many patients believe it does. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, cognitive, deprivation, function, long-term, mental | 4 Comments »
A multi-institutional, international study has provided us with data on the 10-, 15-, and 20-year survival of a cohort of 600 relatively young, high-risk prostate cancer patients, all of whom were treated with first-line radical prostatectomy. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: "high risk", long-term, mortality, outcome, prostatectomy, radical | 14 Comments »
Late last week we commented briefly on a paper (by Darwish-Yassine et al.) entitled “Evaluating long-term patient centered outcomes following prostate cancer treatment: findings from the Michigan Prostate Cancer Survivor study.” … READ MORE …
Filed under: Living with Prostate Cancer, Management | Tagged: complications, long-term, quality of life, side effects, survivorship | 5 Comments »
There are very few really good data available on the long-term follow-up of men diagnosed and treated for prostate cancer outside a select group of specialized prostate cancer centers (with the notable exception of the data collected as part of the CaPSURE initiative). … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: care, long-term, outcome, quality of life, side effects | 2 Comments »
A retrospective analysis has (again, somewhat predictably) shown that adding long-term androgen deprivation therapy (ADT) to dose-escalated radiation therapy improves outcomes of men initially diagnosed with high-risk prostate cancer. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: "high risk", ADT, androgen, deprivation, external beam, long-term, radiation | 30 Comments »
A new article in European Urology offers interesting data on the natural history of localized prostate cancer, based on a cohort of 200+ Swedish patients followed for > 30 years. It is important to note immediately that none of these men was originally diagnosed in the PSA era. They all had some form of symptomatic disease at diagnosis. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: follow-up, long-term, monitoring, natural history, observation | 17 Comments »
A new article just published by Taylor et al. in the Journal of Clinical Oncology provides detailed information about the persistence of clinically significant, long-term, prostate cancer-specific, treatment-related sexual and urinary adverse effects up to 10 years post-diagnosis. Coverage of this article also appears in a report on Reuters.com. … READ MORE …
Filed under: Living with Prostate Cancer, Management | Tagged: adverse effects, long-term, persistence, Treatment | 5 Comments »
In September last year we provided information about a Danish study by Orsted et al. on the use of PSA levels in projecting the long-term risk of prostate cancer that had been presented at a scientific meeting in Europe. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Risk | Tagged: baseline, long-term, PSA, risk | 2 Comments »
A new study in the Journal of Urology reports data on a cohort of 125 patients enrolled in the Physicians’ Health Study (PHS) who elected to be managed with watchful waiting for a minimum of 1 year after their initial diagnosis and who were followed for an average (mean) of 7.3 years. … READ MORE …
Filed under: Management, Treatment | Tagged: active surveillance, long-term, outcome, quality of life, watchful waiting | 8 Comments »
Between 1981 and 1983 researchers collected and stored blood samples from 4,500 men in Copenhagen, Denmark, as part of the Copenhagen City Heart Study. These blood samples had been carefully stored — and otherwise unused — for nearly 30 years. In 2010, a new research team decided to measure the PSA levels in these blood samples. … READ MORE …
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: Diagnosis, long-term, mortality, PSA, risk, screening | 5 Comments »
In 2007, Hans Lilja and colleagues first used data from the Swedish cancer registries and blood banks to demonstrate that a single PSA value in men between 44 and 50 years of age was highly predictive of subsequent prostate cancer diagnosis in an unscreened population. New data now support that original finding, but with a 7-year-longer timeframe. … READ MORE …
Filed under: Diagnosis, Risk, Uncategorized | Tagged: long-term, PSA, risk, screening, testing | 15 Comments »
A study reported this week in the Archives of Internal Medicine addresses the impact of biochemical recurrence on risk for prostate cancer-specific mortality (PCSM) among a cohort of more than 1,000 US veterans initially diagnosed and treated between 1991 and 1995. … READ MORE …
Filed under: Living with Prostate Cancer, Management | Tagged: biochemical recurrence, long-term, outcome, radical prostatectomy, radiotherapy, veteran | 7 Comments »
The complex and common series of significant short- and long-term complications of radical prostatectomy (RP) — whether conducted with or without the assistance of a robot — are often not well understood by patients when they elect this form of treatment for localized prostate cancer. … READ MORE …
Filed under: Management, Treatment | Tagged: complications, long-term, outcomes, radical prostatectomy | Leave a comment »
THE "NEW" PROSTATE CANCER INFOLINK 