After long-term ADT … recovery of normal hormonal function?

A group of Spanish clinical researchers have reported recent data from a small study designed to address an unanswered question about the recovery of (relatively) normal hormonal function after completion of androgen deprivation therapy (ADT). … READ MORE …

Does long-term ADT really affect cognitive function or not?

After > 50 years of use of various forms of androgen deprivation therapy (ADT), we still don’t really have a clear idea of whether or the degree to which long-term, continuous ADT can affect cognitive function — although there is no doubt at all that many patients believe it does. … READ MORE …

Long-term survival of high-risk patients < 60 years of age treated by radical prostatectomy

A multi-institutional, international study has provided us with data on the 10-, 15-, and 20-year survival of a cohort of 600 relatively young, high-risk prostate cancer patients, all of whom were treated with first-line radical prostatectomy. … READ MORE …

Follow-up to earlier commentary on the Michigan Prostate Cancer Survivor study

Late last week we commented briefly on a paper (by Darwish-Yassine et al.) entitled “Evaluating long-term patient centered outcomes following prostate cancer treatment: findings from the Michigan Prostate Cancer Survivor study.” … READ MORE …

Long-term quality of life and survivorship issues for prostate cancer patients

There are very few really good data available on the long-term follow-up of men diagnosed and treated for prostate cancer outside a select group of specialized prostate cancer centers (with the notable exception of the data collected as part of the CaPSURE initiative). … READ MORE …

EBRT + long-term ADT in treatment of men with high-risk, localized prostate cancer

A retrospective analysis has (again, somewhat predictably) shown that adding long-term androgen deprivation therapy (ADT) to dose-escalated radiation therapy improves outcomes of men initially diagnosed with high-risk prostate cancer. … READ MORE …

HBOT for treatment of radiation cystitis consequent to radiation therapy for prostate cancer

A Japanese clinical research team recently published long-term follow-up data from a small series of patients treated with hyperbaric oxygen therapy (HBOT) to alleviate radiation cystitis as a side effect associated with radiation therapy for prostate cancer. … READ MORE …