PET/MRI scanning in pre-surgical staging of high-risk prostate cancer patients

A small, Norwegian, Phase II clinical trial has explored the potential diagnostic value of [18F]fluciclovine PET/MRI scans of the pelvic lymph nodes in staging for patients with high-risk prostate cancer. … READ MORE …

Salvage treatment of recurrent, lymph node-positive prostate cancer in the modern era

The advent of imaging tests like the [11C]choline PET/CT scan and others have made it possible to identify, relatively early, the presence of one or more foci of recurrent prostate cancer after first-line therapy, and often these recurrent foci can be found in patients’ pelvic lymph nodes. … READ MORE …

Pelvic lymph node dissection and robot-assisted laparoscopic radical prostatectomy

With the introduction of robot-assisted laparoscopic radical prostatectomy (RALP) there came suggestions from some surgeons that this technique made pelvic lymph node dissection (PLND) more difficult. However, a new review by a respected international group of authors clearly disagrees with this suggestion. … READ MORE …

Accurate identification of positive lymph nodes in men with progressive prostate cancer

One of the hardest things to be able to do, currently, in a man with progressive prostate cancer after first- or second-line therapy, is to determine his risk for lymph node-positive prostate cancer or LNPPC (i.e., one of the earliest  and more common components of metastatic prostate cancer). … READ MORE …

The demise of Combidex / Sinerem

For several years a company initially called Advanced Magnetics (and later known as AMAG Pharma), with its partners, spent a good deal of money developing and seeking approval of a product called ferumoxtran-10. … READ MORE …

Prostate cancer news reports: Tuesday, June 30, 2009

In todayas news reports we deal with items about:

  • Celecoxib therapy prior to radical prostatectomy for cT1-2 disease
  • Sentinel lymph node dissection (again)
  • Surgical decompression and spinal reconstruction in man with spinal metastasis … READ MORE …

Sentinel lymph node dissection in prostate cancer

A technique known as sentinel lymph node dissection (SLND) has replaced extended lymphadenectomy for nodal staging in several types of solid tumor cancers. … READ MORE …