Understanding “cell-free DNA analysis” in cancer diagnosis and management

We have probably all heard terms like “liquid biopsy” and “genetic screening” and “cell-free” DNA analysis over the past few years. These are all terms related to the use of genetic and genomic information to “personalize” cancer diagnosis and its management. And they are potentially a huge big deal. But, … READ MORE …

But annual, mass, population-based PSA screening really works (or does it?)

A new and potentially controversial article in Urology (the “Gold Journal”) has just suggested that regular, mass, population-based screening of men for risk of prostate cancer every 12 to 18 months remains a good idea. … READ MORE …

Hypothetical cost savings associated with “observation” for low-risk prostate cancer

A newly published article in JAMA Oncology has reported hypothetical costs savings to Medicare of $320 million over a 3-year time frame if men of > 70 years with low-risk prostate cancer are simply “observed” as opposed being given immediate treated. … READ MORE …

Understanding the genetics of prostate cancer diagnosis and treatment

For those who are interested in this evolving topic, we recommend listening to Dr. Charles Ryan’s 16-minute-long discussion with Heather Cheng, MD, PhD, entitled “Genetic evaluation and counseling in prostate cancer treatment”. … READ MORE …

Speed of change in the management of prostate cancer

One of our regular correspondents (who lives in England) was recently told something rather interesting by the Consultant Urologist he sees in the UK. … READ MORE …

Active surveillance in management of younger men with prostate cancer

Your sitemaster has long argued that it is perfectly reasonable for many younger men diagnosed with low- and very low-risk forms of prostate cancer to be managed initially on active surveillance (despite reticence on the parts of many physicians and many patients). … READ MORE …

Prostate cancer and its management: where we are at now

A relatively long article in the June 21 issue of US News & World Report discusses a series of topical issues related to the diagnosis and management of prostate cancer, including: … READ MORE …