A newly proposed way to classify types of prostate cancer progression

An article by a respected group of researchers at the University of Texas M. D. Anderson Cancer Center in Houston, published in the August issue of Cancer Discovery, proposes a new classification system for progression of prostate cancer over time. This has implications for the appropriate development and use of markers for use in treatment and drug development. … READ MORE …

New genetic mechanism explains prostate cancer progression in androgen-suppressed patients

According to a media release from Cancer Research UK yesterday, “The first-ever comprehensive study of prostate cancer tissue has revealed a completely new gene network driving the disease in patients who have stopped responding to standard hormone treatment.” … READ MORE …

How abiraterone acetate actually works in advanced prostate cancer

A regular reader of this column asked us to provide a “layman’s summary” of how the investigational drug abiraterone acetate actually works to delay the progression of metastatic, castration-resistant prostate cancer (mCRPC). So here you go … READ MORE …

A whole new way for testosterone to reach the prostate?

It has long been clear that testosterone has an essential function in regulating the behavior of prostate tissues and has significant impact on the development and progression of prostate cancer. However, the way in which testosterone exerts these effects (the pathophysiological mechanism of prostate cancer) is still not well established or well understood. … READ MORE …

The Friday news reports: January 9, 2009

There are a number of rather technical reports in the news today, and we summarize these briefly below, providing the usual links to the abstracts for readers who are interested. In a separate report we have addressed the development of a new nomogram that can be used to predict risk for early disease progression following radical prostatectomy for localized disease. … READ MORE …

The Christmas day news: December 25, 2008

The Christmas day news is based on four review articles encompassing:

  • New molecular markers for prostate cancer diagnosis
  • The incidence of prostate cancer in China
  • The treatment of “locally advanced” prostate cancer in the UK
  • The mechanism of prostate cancer metastasis … READ MORE …