Complementary and alternative medicines in management of prostate cancer

A newly published paper in the Journal of Urology has reported on the use of complementary and alternative medicines (CAMs) among a cohort of nearly 8,000 American patients with a diagnosis of prostate cancer between 1996 and 2016. … READ MORE …

Precision medicine and primary Gleason pattern 5 prostate cancer

Patients who are initially diagnosed with primary Gleason pattern 5 localized prostate cancer (i.e., having Gleason scores of 5 + 5 = 10 and 5 + 4 = 9) are well understood to have very high-risk disease. … READ MORE …

Computer modeling, genomics, and prostate cancer prognosis

A newly published paper on the development of prostate cancer in patients of ≤ 55 years of age claims to have shown that

Using a newly-developed computer model, it is now possible to predict the course of the disease in individual patients. … READ MORE …

Experts create guidelines for screening prostate cancer patients for inherited cancer risk genes

Knowing whether you carry inherited cancer risk genes can help you to make the best decisions for your treatment and for your family. … READ MORE …

Commercially available liquid biopsy data may be misleading

A newly published research letter in JAMA Oncology is entitled “Patient-paired sample congruence between 2 commercial liquid biopsy tests”. The two tests are both said — by the companies that market them — to have high clinical sensitivity and specificity in the identification of specific genetic markers associated with high-risk forms of prostate cancer. … READ MORE …

Alternative medicine in the treatment of cancer (prostate cancer included)

There are very few good and thorough clinical studies on the use and the long-term effectiveness or efficacy of alternative forms of medicine in the treatment of cancer (let alone the treatment of prostate cancer specifically). … READ MORE …

How close are we really to “precision medicine” for cancer care?

A newly published paper in the journal JCO Precision Oncology confirms what many of us may have suspected — that the practical application of somatic tissue testing to clinical decision-making was low prior to 2015 . … READ MORE …

More in the new Everyday Urology-Oncology Insights

Last week we had let readers know about a new, straightforward, on-line review journal called Everyday Urology-Oncology Insights. … READ MORE …

Of moonshots, precision medicine, and progress in the management of cancer

As your sitemaster, let me be very clear about a couple of my most basic beliefs about prostate cancer and prostate cancer research. I want to do this because of all the recent media discussion about Vice President Byden’s “Moonshot” and the possible wonders of precision medicine. … READ MORE …

Are you a good candidate for the TAPUR study? If so, sign up!

Nearly a year ago now, the American Society of Clinical Oncology (ASCO) first announced plans to initiate an innovative trial of a personalized medicine initiative called the Targeted Agent and Profiling Utilization Registry (TAPUR) study. … READ MORE …

What IS an “N-of-1” clinical trial?

As we come, slowly, closer and closer to truly individualized forms of medical practice, in which individual patients get treated individually based not just on “what works” for most men with (say) prostate cancer that has just progressed to the metastatic stage, clinical researchers are increasingly interested in so-called “N-of-1″ clinical trials. … READ MORE …

CRPC, “personalized” medicine, and the science of whack a mole

We have known for decades that prostate cancer is an “evolutionary” cancer. In other words, clinically significant prostate cancer and prostate cancer-specific mortality are the consequence of a series of events over time (probably both genetic and epigenetic) that lead to progressive and then to metastatic disease of variable levels of aggression. … READ MORE …

Just how helpful is personalized genomic analysis anyway?

Regular readers of the medical science literature will be very conscious of the emphasis on genomic analysis of tumor specimens as a way to try to “personalize” treatment of cancers of many types — prostate cancer very specifically included. … READ MORE …

More good info in the GU Cancers Symposium “Daily News”

The print and online “Daily News” provided by the organizers of the Genitourinary Cancers Symposium here in Orlando offers additional articles today that may be of interest to many InfoLink readers. … READ MORE …

Complementary and alternative medicine and prostate cancer care

The current issue of Urologic Clinics of North America, edited by Mark Moyad, MD, of the University of Michigan Medical Center, includes a series of review articles dealing with complementary and alternative care in the prevention and management of urologic disorders in general and prostate cancer in particular. … READ MORE …