Projecting the need for confirmatory biopsies in candidates for active surveillance

A newly published paper from the Memorial Sloan-Kettering Cancer Center group in New York has proposed a predictive model which might allow a high percentage of candidates for active surveillance as initial management to skip a second, confirmatory biopsy after initial diagnosis. … READ MORE –

Along with robotic surgery come … 3D printed prostate models?

So a research study from the Keck School of Medicine of the University of Southern California has provided some very preliminary information about the utility of 3D printed models as surgical aids to radical prostatectomy. … READ MORE …

The prevalence, incidence, and mortality of specific sets of prostate cancer patients by 2020

A newly published paper in the journal PLoSOne has addressed the future prevalence of various different clinical states of prostate cancer here in the USA, along with the mortality of the men diagnosed with prostate cancer. … READ MORE …

The complexity of assessment of prostate cancer risk

A new study just published online in the journal Cancer Discovery has helped to clarify — or perhaps “clarify” is the wrong word — just how complex risk for prostate cancer really is. … READ MORE …

Development of prostate cancer “organoids” may facilitate next-gen research

Researchers at Weill Medical College and at Memorial Sloan-Kettering Cancer Center in New York have worked out how to grow “organoids” from metastatic prostate cancer tissue. This may be important for the clinical testing of new types of treatment and (later on) for the ability to determine which drugs work well in individual patients. … READ MORE …

A long way from actual clinical applicability, but interesting anyway …

There was an intriguing paper in the November 2013 issue of the journal Prostate suggesting that intermittent dosing with testosterone in between doses of androgen deprivation therapies may actually help men in the early stages of castration resistance to respond better to treatment over time. … READ MORE …

A newly proposed way to classify types of prostate cancer progression

An article by a respected group of researchers at the University of Texas M. D. Anderson Cancer Center in Houston, published in the August issue of Cancer Discovery, proposes a new classification system for progression of prostate cancer over time. This has implications for the appropriate development and use of markers for use in treatment and drug development. … READ MORE …