30 years follow-up of men with initially untreated, localized prostate cancer

A new article in European Urology offers interesting data on the natural history of localized prostate cancer, based on a cohort of 200+ Swedish patients followed for > 30 years. It is important to note immediately that none of these men was originally diagnosed in the PSA era. They all had some form of symptomatic disease at diagnosis. … READ MORE …

The natural history of biochemical recurrence after surgery

It has been well understood for years that biochemical recurrence (BCR) after radical prostatectomy does not always translate into systemic progression or necessarily lead to prostate cancer metastasis and death. The “natural history” of BCR is actually very variable. … READ MORE …

The natural history of low-risk prostate cancer

In a presentation given at the annual meeting of the American Urology Association earlier this year, researchers from Memorial Sloan-Kettering Cancer Center (MSKCC) provided some interesting data on the natural history of prostate cancer in patients initially diagnosed with low-risk disease. … READ MORE …