Can MRI data improve older, pre-treatment, prognostic methods?

An obvious but previously unanswered question has been whether adding data from the results of MRI scans to the data used in the Partin tables and in the pre-surgical Kattan nomogram (also known as the Memorial-Sloan Kettering Cancer Center or MSKCC nomogram) can improve the accuracy of these two commonly used prognostic methods. … READ MORE …

Probability of remaining recurrence-free after salvage radiation

Nearly 10 years ago, in 2007, Stephenson et al. published a nomogram that predicted the probability of success of salvage radiation therapy (SRT) after post-prostatectomy biochemical failure. … READ MORE …

The dangers of using nomograms to compare apples to oranges

A cross-specialty group of prostate cancer experts has reviewed data from > 13,000 patients on the accuracy of nomograms in predicting biochemical recurrence and actual prostate cancer-specific mortality after three different types of treatment. … READ MORE …

Predicting outcomes after early salvage radiation therapy for locally recurrent disease

A international, collaborative research group has but together a new nomogram designed to project outcomes at 5 years after early salvage radiation therapy (eSRT) for men with local disease recurrence after first-line surgery for localized prostate cancer. … READ MORE …

Can we accurately project risk for over-diagnosis and over-treatment?

There is an interesting new article just published in the Journal of the National Cancer Institute describing a nomogram designed to estimate risk for over-diagnosis of men diagnosed with prostate cancer. … READ MORE …

Nomograms projecting risk for upgrading in lower-risk forms of prostate cancer

We are starting to see the development of nomograms that can be used to project the risk for future upgrading of men who are diagnosed with very low- and low-risk prostate cancer and who initially meet criteria for active surveillance as a first-line management strategy. … READ MORE …

Clinical use of nomograms and other tools in prostate cancer counseling and prognosis

Clinical guidelines from such organizations as the American Urological Association (AUA) and the National Comprehensive Cancer Network (NCCN) call for measures designed to improve quality of care and facilitate better treatment decisions for men newly diagnosed with prostate cancer. The degree to which this really happens, however, is not well understood. … READ MORE …