Risk for prostate cancer diagnosis from the Finnish Prostate Cancer Screening Trial

A new paper in the Scandinavian Journal of Urology has provided us with some insights into things associated (and not associated) with risk for a diagnosis of prostate cancer, based on data from > 12,000 participants in the Finnish cohort of the European Randomized Screening for Prostate Cancer (ERSPC) study. … READ MORE …

VITAL says NSAIDs not effective in prostate cancer prevention

Data from the VITAL cohort study do not support the use of non-steroidal anti-inflammatory drugs (NSAIDs) in the chemoprevention of prostate cancer, according to a newly published study. … READ MORE …

Effects of common medications on likelihood of prostate cancer diagnosis

It has been known for a while that statins and nonsteroidal anti-inflammatory drugs (NSAIDs) can affect PSA levels. A new paper now opens the question of whether men who take these and/or other drugs for significant time periods are at risk for a “missed” diagnosis of prostate cancer. … READ MORE …

No clinical evidence that NSAIDs help to prevent prostate cancer

Data gathered as part of the ongoing ProtecT study in the United Kingdom provides no evidence that regular use of non-steroidal anti-inflammatory drugs l(NSAIDs) lowers risk for prostate cancer. … READ MORE …

Of statins, NSAIDs, and “all-cause” mortality in prostate cancer patients

There have been a lot of data published on the potential implications of long-term use of statins (e.g., simvastatin/Zocor and atorvastatin/Lipitor) and non-steroidal antianflammmatory drugs (NSAIDs, e.g.,  aspirin and ibuprofen) in prevention and management of prostate cancer. But what we are really sure of at the moment is limited. … READ MORE …

Long-term statin/NSAID use and mortality of prostate cancer patients

Many papers have previously suggested an association between the long-term use of statins (e.g., simvastatin/Zocor and atorvastatin/Lipitor) or nonsteroidal anti-inflammatory drugs (NSAIDs, like aspirin), the risk of prostate cancer diagnosis, and the overall survival of men diagnosed with prostate cancer. … READ MORE …

The impact of NSAID use on PSA level and prostate cancer diagnosis

Over the years there have been several studies suggesting that regular use of non-steroidal anti-inflammatory agents (NSAIDs) — the most common being aspirin — can decrease prostate inflammation and prostate cancer risk. Since aspirin and other NSAIDs are commonly used to prevent cardiovascular disease, it will be apparent that there is going to be relatively high use of these agents in the men who are also at some degree of risk for prostate cancer. … READ MORE …