A newly published article in JAMA Oncology has reported hypothetical costs savings to Medicare of $320 million over a 3-year time frame if men of > 70 years with low-risk prostate cancer are simply “observed” as opposed being given immediate treated. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: conservative, cost, Management, Medicare, observation, saving | Leave a comment »
A report in the journal Urology (the so-called “Gold Journal”) from a team of researchers at Yale School of Medicine has shown that having a prostate MRI as part of the work-up for a patient initially diagnosed with low-risk prostate cancer roughly doubled the chance that such a patient was initially managed on “observation”. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: active surveillance, monitoring, MRI, observation, risk, scan | 2 Comments »
A new article in this week’s New England Journal of Medicine has given us follow-up data from the PIVOT trial of radical prostatectomy vs. simple observation in treatment of localized prostate cancer. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: localized, observation, outcomes, PIVOT, surgery, trial | 4 Comments »
Five years ago now, in May 2011, Wilt first presented the results of the PIVOT trial at the annual meeting of the American Urological Association in Washington, DC. A bit over a year later, the final results were published in the New England Journal of Medicine. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: observation, outcomes, PIVOT, surgery | 6 Comments »
A new article by Maurice et al. in the Canadian Urological Association Journal provides detailed information about the use of initial observation as a management strategy for low-risk prostate cancer between 2004 and 2011. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management | Tagged: active surveillance, low risk, Management, observation, watchful waiting | 2 Comments »
As many of our regular readers will know, there is no clear answer to the question whether, among men at elevated risk of progressive disease after first-line surgery, it is better to have adjuvant radiation therapy (ART) within a few months of surgery or to wait until salvage radiation therapy (SRT) is clearly advisable. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Risk, Treatment | Tagged: adjuvant, observation, radiation, risk, salvage, surgery | 1 Comment »
In an article in Recent Results in Cancer Research, Wilt argues (yet again) that “observation” (i.e., something less than active surveillance and perhaps more like “watchful waiting”) is an entirely appropriate way to manage selected men with low-risk prostate cancer. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: observation, PIVOT, watchful waiting | 8 Comments »
A newly published study in the Annals of Internal Medicine has offered an analysis of the cost-effectiveness of “observation” as compared to immediate initial treatment for men diagnosed with low-risk, localized prostate cancer. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Uncategorized | Tagged: active surveillance, cost, life, low risk, observation, quality, quantity, Treatment, watchful waiting | 4 Comments »
A new article in European Urology offers interesting data on the natural history of localized prostate cancer, based on a cohort of 200+ Swedish patients followed for > 30 years. It is important to note immediately that none of these men was originally diagnosed in the PSA era. They all had some form of symptomatic disease at diagnosis. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: follow-up, long-term, monitoring, natural history, observation | 17 Comments »
Yesterday we suggested that we would have more to say about this study when we had read the full text of the article by Wilt et al. and the associated editorial by Thompson and Tangen. However, in all truth, others have really done this job for us, and there is little point in reinventing the wheel. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Risk, Treatment | Tagged: observation, outcome, PIVOT, surgery | 10 Comments »
The complete results of the Prostate Cancer Intervention versus Observation Trial (PIVOT) study have (finally) just been published in the New England Journal of Medicine. Unfortunately, only the abstract is available on line so it may take us a little while to get hold of a copy of the complete report. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: observation, outcome, PIVOT, radical prostatectomy | 10 Comments »
Many readers may be interested in an article on active surveillance and other forms of expectant management by Khurana and Stephenson that appears on the front page of the November issue of the AUA News. This article is based on a poster presented by Khurana et al. at the annual meeting of the American Urological Association earlier this year.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: active surveillance, expectant management, observation, watchful waiting | 1 Comment »
A new report in European Urology may offer some insights into the value of large, retrospective data analyses as compared to multi-center, randomized clinical trials when it comes to the assessment of the effects of different first-line treatments on the management of clinically localized prostate cancer. … READ MORE …
Filed under: Management, Treatment, Uncategorized | Tagged: age, mortality, observation, radical prostatectomy, watchful waiting | 5 Comments »
So Dr. Timothy Wilt presented the initial results of the Prostate Cancer Intervention Versus Observation Trial (PIVOT) at the annual meeting of the AUA yesterday morning. They showed what many of us may have been expecting. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: benefit, observation, outcome, PIVOT, surgery | 22 Comments »
THE "NEW" PROSTATE CANCER INFOLINK 