Is there an “oligometastatic state” for prostate cancer?

The concept of an “oligometastatic state” is based on the idea that there is an “early advanced” stage of cancer during which metastases are few in number and are in some way different from metastases that develop later. … READ MORE …

Improving survival among men with oligorecurrent prostate cancer?

A newly published article in the Journal of Clinical Oncology reports data from a small, randomized, multicenter, Phase II clinical trial comparing active monitoring to treatment of men with recurrent, asymptomatic, oligometastatic prostate cancer. … READ MORE …

Current trends in the management of oligometastatic prostate cancer

In what one of the authors has described as “a somewhat critical and light-hearted look at our current enthusiasm for aggressive approaches to oligometastatic prostate cancer”, an article currently in press asks some serious questions about the use of metastasis-directed therapy or MTD in the management of such patients. … READ MORE …

Targeting treatments for extraprostatic and oligometastatic prostate cancer with curative intent

The moderator of a well-known, prostate cancer-specific Internet forum recently wrote to us, stating,

There has been some assumption on the part of users of internet patient forums that the [newer and] more sensitive scans can be useful to detect major tumors that can be removed laparoscopically or treated with radiation, and that this would be beneficial.

… READ MORE …

SBRT for oligometastatic recurrence

Although the theory of the existence of a temporarily stable oligometastatic stage in prostate cancer is more than 20 years old, it remains unknown whether there is any benefit to pursuing curative or progression-delaying radiation (or indeed other forms of targeted treatment) if there are only a few metastases detected at recurrence. … READ MORE …