Outcomes of 55 men who had prophylactic RALPs for suspicion of unproven prostate cancer

Over the years, we have been asked several times whether there is a role for any type of  immediate treatment in men with a high level of concern for their risk of prostate cancer — despite a negative finding on prostate biopsy. … READ MORE …

Very early salvage radiation has up to fourfold better outcomes and saves lives

Another subject that has come up a lot recently is when to have salvage radiation. It is always a pressing decision for those 30 percent of prostatectomy patients who have detectable PSA after prostatectomy. … READ MORE …

Patient-reported outcomes and quality of life in the ProtecT trial

We have already commented on the oncologic outcomes of patients enrolled in the ProtecT trial and published in today’s issue of the New England Journal of Medicine. In this commentary we shall comment on the separate paper that addresses patient-reported outcomes from that trial. … READ MORE …

The initial (10-year) results of the ProtecT trial: much as we might have expected?

So the majority of the readers of The “New” Prostate Cancer InfoLink will be well aware that we have never had data from a large, randomized clinical trial comparing the outcomes of the commonest first-line forms of management of men diagnosed with localized prostate cancer … READ MORE …

Most recurrences after primary radiation failure are salvageable

Salvage therapy is curative in about half of the men who have a biochemical failure after primary therapy for localized prostate cancer. That’s true whether the primary therapy was surgery or radiation. … READ MORE …

RALP vs. open surgery: “similar functional outcomes at 12 weeks”

Back in July we reported the initial publication on line of the results of a randomized Phase III trial by Yaxley et al. that compared the initial outcomes of open radical retropubic prostatectomy to robot-assisted laparoscopic prostatectomy (RALP). This paper has now been published by The Lancet along with two sets of editorial commentary. … READ MORE …

Very long-term response to antiandrogen withdrawal in metastatic prostate cancer

Confirming just how strange prostate cancer can actually be sometimes, here is a very unusual case history associated with antiandrogen withdrawal from a group of Japanese researchers. … READ MORE …