As we have seen, stereotactic body radiation therapy (SBRT) is a preferred therapy for low- and intermediate-risk patients (see this link). It is effective, safe, convenient, and relatively inexpensive. However, its use for high-risk patients remains controversial. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: "high risk", intermediate risk, outcomes, radiation | 5 Comments »
To date we have seen very few data on the long-term follow-up of men in the US being initially managed on active surveillance (AS) after diagnosis with prostate cancer out in the “real world” of community urology practice. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: active surveillance, AS, community, outcomes, practice | 1 Comment »
A recent paper from a large Swedish research group has addressed patient satisfaction and the management of localized prostate cancer — with a specific, inclusive focus on the satisfaction of men initially managed on active surveillance. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: outcomes, patient, QOL, quality. life, satisfaction | 2 Comments »
Meier et al. have just published updated results of a 5-year multi-institutional trial finding that stereotactic body radiation therapy (SBRT) had high rates of cancer control and low toxicity. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: bod, outcomes, radiation, SBRT, stereotactic | 6 Comments »
A critical question for men with favorable intermediate-risk prostate cancer (based primarily on a Gleason score of 3 + 4 = 7) can often be, “How safe would it be for me to go on active surveillance for a while after initial diagnosis?” … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: active surveillance, outcomes, risk, surgery | 20 Comments »
Back in the early 1980s, Dr. Patrick Walsh at the Johns Hopkins Medical Center in Baltimore changed the nature of surgical treatment for prostate cancer when he first started to conduct so-called nerve-sparing radical prostatectomies. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: outcomes, prostatectomy, radical, Retzius-sparing | 7 Comments »
A new article in this week’s New England Journal of Medicine has given us follow-up data from the PIVOT trial of radical prostatectomy vs. simple observation in treatment of localized prostate cancer. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: localized, observation, outcomes, PIVOT, surgery, trial | 4 Comments »
We now have data from an eighth randomized clinical trial of hypofractionated radiation therapy. There are no surprises: … READ MORE …
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: hypofractionation, outcomes, radiation | Leave a comment »
In September last year, Hamdy et al. published the initial results of the ProtecT trial — a trial designed to compare overall outcomes at 10 years among > 1,600 men diagnosed with low- and intermediate-risk, localized prostate cancer and randomized to treatment by surgery, by external beam radiation therapy, or by active monitoring (a very basic form of active surveillance). … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Treatment | Tagged: outcomes, ProtecT, radiation, surgery, trial. monitoring | Leave a comment »
So the results from the CHAARTED and STAMPEDE trials over the past few years have re-ignited debate over the appropriateness of early use of chemotherapy in the treatment of aggressive forms of prostate cancer. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: "high risk", aggressive, chemotherapy, early, outcomes | 1 Comment »
It is well understood that there is an association between obesity and future risk for prostate cancer-specific mortality among cancer-free men. What has not been so clear is the relationship between obesity and long-term outcomes, post-treatment, among men diagnosed early with localized disease … READ MORE …
Filed under: Living with Prostate Cancer, Management, Risk, Treatment | Tagged: BMI, mortality, obesity, outcomes, overweight, radical prostatectomy | 2 Comments »
I was reticent to write about hypofractionation yet again after writing about it so often in the last year (see this link for my latest summary). … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: hypofractionation, IMRT, outcomes, radiation, therapy | 1 Comment »
There is a “conventional wisdom” that active surveillance (AS) is only for older men, and that younger men are better off having immediate radical treatment, typically prostatectomy (RP). …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: active surveillance, comparion, immediate, life, outcomes, quality, Treatment | 10 Comments »
We have previously reported on the very good, albeit unremarkable, outcomes of proton beam radiation therapy (PBRT) as administered at the University of Florida Jacksonville. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: comparison, outcomes, PBRT, proton, therapy | 4 Comments »
THE "NEW" PROSTATE CANCER INFOLINK 