Two phase III trials planned for cabozantinib in mCRPC

Accoring to a Bloomberg Businessweek report and information on the Exelixis corporate web site, the company is planning two multi-center, randomized, Phase III clinical trials of the investigational agent cabozantinib (a.k.a., XL184) in metastatic, castration-resistant prostate cancer (mCRPC): … READ MORE …

Ibandronate for relief of pain in men with metastatic prostate cancer

According to another study presented at the European Multidisciplinary Cancer Congress (EMCC) in Stockholm this weekend, the bone-strengthening bisphosphonate ibandronate (Boniva®) seems to work just as well as radiotherapy for the management of pain associated with prostate cancer that has metastasized to the bones. … READ MORE …

Oncogenex makes SATURN trial of custirsen (OGX-011) more accessible

The Phase III SATURN clinical trial of OGX-011 in treatment of men with metastatic, castration-resistant prostate cancer (mCRPC) after initial chemotherapy with docetaxel + prednisone required men to be randomized to either docetaxel + prednisone + OGX-011 or to docetaxel + prednisone + a placebo. … READ MORE …

The right way to deliver palliative radiation therapy for pain management

It has come to our attention that the American Society for Radiation Oncology (ASTRO) has developed new guidance on the use of palliative external beam radiation therapy (EBRT) for the management of pain associated with metastasis of cancer to bone — a relatively common problem in late stage, metastatic prostate cancer. … READ MORE …

The weekend news report: April 25, 2009

So before I run out the door to get my plane to Chicago, here are non-AUA reports on:

  • Perspectives on applications of PSA data in diagnostic profiling
  • The adverse events of androgen deprivation therapy
  • Potential new form of pain management in very late stage disease … READ MORE …

The news report: Wednesday, April 22

Today’s news reports deal with:

  • A gene modification that may identify risk for prostate cancer
  • Dietary intervention and prostate cancer management
  • “Elastography” as a possible means to assess risk for prostate cancer
  • Pain management in very late stage disease … READ MORE …