Axumin-based PET/CT scans and detection of recurrent prostate cancer

A new report from a relatively small, single-institution study has provided additional information about the utility of [18F]fluciclovine (Axumin) PET/CT scans in the detection of recurrent prostate cancer after definitive first-line treatment. … READ MORE …

Imaging studies for men with recurrent prostate cancer

We had previously reported on a presentation by Calais et al. earlier this year. … READ MORE …

Gallium-68 PSMA vs. fluorine-18 fluciclovine PET/CT scans

According to a presentation given yesterday at the ASCO meeting here in Chicago, PET/CT scanning with 68Ga-PSMA-11 is more accurate than 18F-fluciclovine PET/CT at detecting recurrent prostate cancer in men with early biochemical recurrence following radical prostatectomy. … READ MORE …

How accurate are gallium-68 PSMA PET/CT scans in the “real world”?

A new article in the journal Cancer Imaging has provided us with an interesting set of “real world” data on the accuracy of gallium-68 PSMA PET/CT scans in the management of prostate cancer. … READ MORE …

Copper-64 PET/CT scanning for biochemically relapsing prostate cancer

A group of Italian researchers have apparently shown that a copper-64 dichloride-based radiotracing agent (64CuCl2) is better than currently-used 18FCl radiotracers in the detection of biochemically recurrent prostate cancer with PET/CT scans … READ MORE …

Use of mpMRI and PSMA PET/CT to aid in salvage radiation decision-making

Because the success or failure of salvage radiation (SRT) hinges upon whether micrometastases are already systemic at the time of treatment, evidence that the cancer is still local improves the odds that SRT will be successful. … READ MORE …

Carbon-11-labeled sarcosine as a prostate cancer imaging agent

A new paper in the Journal of Nuclear Medicine has reported the first use of [11C]sarcosine in combination with PET/CT scanning as a technique for imaging prostate cancer in man. … READ MORE …

Gallium-68 PSMA PET/CT scans changed management in 39 percent of patients

The gold standard for the clinical relevance of any new test in the management of a specific disease is … Do the results of the test change the way a physician would previously have managed patients? … READ MORE …

Are two PET radiotracers better than one?

There seem to be clinical trials of new PET radiotracers for the detection of prostate cancer all the time. In addition to the FDA-approved [11C]choline, Na18F, FDG, and fluciclovine PET scans, most of the new PET scans target the PSMA protein on prostate cancer cells. … READ MORE …

Comparison of gallium-68- and choline-C11-based PET/CT scanning in high-risk and progressive prostate cancers

The question of how much better the varied, new forms of imaging will be in the evaluation of patients with higher-risk prostate cancer both before and after their treatment is a currently “hot topic” in the world of prostate cancer. … READ MORE …

Efficacy and safety in the curative treatment of progressive, lymph node-positive prostate cancer

The salvage treatment of men found to have positive lymph nodes after prior (surgical) treatment and the identification of such positive lymph nodes using techniques such as [11C]choline PET/CT scans is still not well established, but it does offer opportunity for some men. … READ MORE …

Can gallium-68-PSMA PET/CT scans change radiation treatment decisions?

A diagnostic or prognostic technique is valuable only insofar as it is able to change treatment decisions. A small Australian study claims that gallium-68-PSMA  ([68Ga]PSMA) PET/CT scans could do this in about half the cases examined. … READ MORE …

The utility and value of new imaging techniques in advanced prostate cancer

PET/CT scans using the radioactive fluorinated inhibitor of prostate-specific membrane antigen (PSMA) known as 18F-DCFBC (or just DCFBC) are better at detecting metastases … READ MORE …

Newer types of whole body scanning are likely to be significantly better than older bone scans, but …

A new report in the Journal of Nuclear Medicine has suggested that it may be time to start looking seriously at whether the combined [18F]NaF/[18F]FDG PET/CT scan may be significantly better than the traditional [99m]Tc bone scan in evaluation of risk for or the actual presence of metastasis in men with prostate cancer. … READ MORE …

Salvage treatment of recurrent, lymph node-positive prostate cancer in the modern era

The advent of imaging tests like the [11C]choline PET/CT scan and others have made it possible to identify, relatively early, the presence of one or more foci of recurrent prostate cancer after first-line therapy, and often these recurrent foci can be found in patients’ pelvic lymph nodes. … READ MORE …