Updated PIVOT data seem to support recent AUA/ASTRO/SUO guidelines

A new article in this week’s New England Journal of Medicine has given us follow-up data from the PIVOT trial of radical prostatectomy vs. simple observation in treatment of localized prostate cancer. … READ MORE …

A look back at PIVOT … with additional data for context

Five years ago now, in May 2011, Wilt first presented the results of the PIVOT trial at the annual meeting of the American Urological Association in Washington, DC. A bit over a year later, the final results were published in the New England Journal of Medicine. … READ MORE …

“Observation” in the management of low-risk prostate cancer

In an article in Recent Results in Cancer Research, Wilt argues (yet again)  that “observation” (i.e., something less than active surveillance and perhaps more like “watchful waiting”) is an entirely appropriate way to manage selected men with low-risk prostate cancer. … READ MORE …

Further comment on the final results of the PIVOT study

Yesterday we suggested that we would have more to say about this study when we had read the full text of the article by Wilt et al. and the associated editorial by Thompson and Tangen. However, in all truth, others have really done this job for us, and there is little point in reinventing the wheel. … READ MORE …

Full publication of the results of the PIVOT study

The complete results of the Prostate Cancer Intervention versus Observation Trial (PIVOT) study have (finally) just been published in the New England Journal of Medicine. Unfortunately, only the abstract is available on line so it may take us a little while to get hold of a copy of the complete report. … READ MORE …

All the PIVOT trial hype from Europe

There has been a lot of media hype in Europe around the re-presentation of the PIVOT data by Dr. Wilt at the annual meeting of the European Association of Urology in Paris last week. And yet every prostate cancer specialist attending that meeting must have already been well aware of these data. … READ MORE …

The initial results of the PIVOT study

So Dr. Timothy Wilt presented the initial results of the Prostate Cancer Intervention Versus Observation Trial (PIVOT) at the annual meeting of the AUA yesterday morning. They showed what many of us may have been expecting. … READ MORE …