A small, Norwegian, Phase II clinical trial has explored the potential diagnostic value of [18F]fluciclovine PET/MRI scans of the pelvic lymph nodes in staging for patients with high-risk prostate cancer. … READ MORE …
Filed under: Diagnosis, Management, Risk | Tagged: Axumin, detection, lymph node, positive, risk, scan | 1 Comment »
Is it still worthwhile to attempt salvage radiation therapy (SRT) after positive pelvic lymph nodes (PLN) have been pathologically detected (stage pN1)? … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: ADT, lymph, node, pN1, positive, radiation, salvage, stage, therapy | 1 Comment »
Really sound guidance on “the best” way to treat men who are initially diagnosed with lymph node-positive (TxN1M0) prostate cancer — or are found to have such cancer at the time of first-line surgery — is not as readily available as one might like. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: lymph, Management, node, outcome, positive, Treatment | 4 Comments »
… know the Gleason score of the tissue at that positive surgical margin as well as and as opposed to just the Gleason score of the primary tumor. It makes a difference to your risk for biochemical recurrence. Your doctors need to know this information too! … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: Gleason, margin, positive, recurrence, risk, score, size, surgical | 12 Comments »
A new paper by a group of German researchers and clinicians has provided us with expanded insight into risk for biochemical recurrence for men with organ-confined prostate cancer and a positive surgical margin based on their post-surgical pathology report. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical, margin, positive, recurrence, risk, surgery | 1 Comment »
The advent of imaging tests like the [11C]choline PET/CT scan and others have made it possible to identify, relatively early, the presence of one or more foci of recurrent prostate cancer after first-line therapy, and often these recurrent foci can be found in patients’ pelvic lymph nodes. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: choline, lymph node, PET/CT, positive, recurrent, salvage, Treatment | 10 Comments »
Could more intensive monitoring of PSA levels in the first few months after a radical prostatectomy help to determine which patients who have a positive surgical margin (PSM) need adjuvant radiation therapy and which don’t? … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: follow-up, margin, positive, PSA, surgery, surgical | 4 Comments »
One of the hardest things to be able to do, currently, in a man with progressive prostate cancer after first- or second-line therapy, is to determine his risk for lymph node-positive prostate cancer or LNPPC (i.e., one of the earliest and more common components of metastatic prostate cancer). … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: accuracy, identification, imaging, lymph node, positive, test | 5 Comments »
In recent years it has become increasingly widely accepted that clinical stage is of dubious value as a prognostic factor in determining prostate cancer risk, particularly as regards the sub-stages of clinical stage T2 (i.e., T2a, T2b, and T2c) in men with localized prostate cancer. … READ MORE …
Filed under: Diagnosis, Management, Risk | Tagged: biopsy, cores, localized, positive, PPC, staging | 10 Comments »
A new study just published in BJU International offers data suggesting the idea that all men found to have positive seminal vesicles (SV+) after radical prostatectomy should receive immediate adjuvant treatment with external beam radiation and androgen deprivation therapy (ADT). … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: adjuvant, ADT, androgen deprivation, positive, radiation therapy, seminal vesicle | 40 Comments »
There are no absolute guidelines as to which patients who have positive surgical margins after a radical prostatectomy (RP) are most appropriate for immediate adjuvant radiation therapy (with or without neoadjuvant and/or adjuvant hormone therapy). … READ MORE …
Filed under: Management, Treatment | Tagged: adjuvant, margin, outcome, positive, radiation, radical prostatectomy | 3 Comments »
So lots of posters and and presentations this morning, but not a lot of actionable information for patients (as far a we could tell). Among the more interesting papers were the following: … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: Gleason score, MDV3100, mortality, OGX-011, positive, risk, surgical. margin | Leave a comment »
An interesting research question is whether, given the earlier diagnosis, the reduced risk for positive surgical margins, and the reduced likelihood of positive lymph nodes at the time of diagnosis in the contemporary PSA era, there has been any impact on the long-term outcomes of men with pathologic T3b prostate cancer post-surgery. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: outcome, positive, pT3b, seminal vesicle, surgery | 11 Comments »
A new study has clearly shown that men with lighter (and therefore smaller) prostates are at greater risk for positive surgical margins after robot-assisted laparoscopic prostatectomy (RALP) than men with heavier (and therefore larger) prostates. … READ MORE …
Filed under: Management, Treatment | Tagged: margin, positive, PSM, risk, volume, weight | Leave a comment »
A new study has suggested that, although the PCA3 test is slightly better than the total PSA test in prediction of risk for a positive biopsy finding, it is not necessarily always better than the free PSA test. … READ MORE …
Filed under: Diagnosis, Risk | Tagged: biopsy, free, PCA3, positive, PSA, risk, total | 1 Comment »
