PET/MRI scanning in pre-surgical staging of high-risk prostate cancer patients

A small, Norwegian, Phase II clinical trial has explored the potential diagnostic value of [18F]fluciclovine PET/MRI scans of the pelvic lymph nodes in staging for patients with high-risk prostate cancer. … READ MORE …

Salvage whole pelvic radiation after cancerous pelvic lymph nodes have been found

Is it still worthwhile to attempt salvage radiation therapy (SRT) after positive pelvic lymph nodes (PLN) have been pathologically detected (stage pN1)? … READ MORE …

The “right” ways to treat TxN1M0 disease today

Really sound guidance on “the best” way to treat men who are initially diagnosed with lymph node-positive (TxN1M0) prostate cancer — or are found to have such cancer at the time of first-line surgery — is not as readily available as one might like. … READ MORE …

If you have positive surgical margins post-surgery, you need to …

… know the Gleason score of the tissue at that positive surgical margin as well as and as opposed to just the Gleason score of the primary tumor. It makes a difference to your risk for biochemical recurrence. Your doctors need to know this information too! … READ MORE …

Biochemical recurrence among pT2 patients with a positive surgical margin post-surgery

A new paper by a group of German researchers and clinicians has provided us with expanded insight into risk for biochemical recurrence for men with organ-confined prostate cancer and a positive surgical margin based on their post-surgical pathology report. … READ MORE …

Salvage treatment of recurrent, lymph node-positive prostate cancer in the modern era

The advent of imaging tests like the [11C]choline PET/CT scan and others have made it possible to identify, relatively early, the presence of one or more foci of recurrent prostate cancer after first-line therapy, and often these recurrent foci can be found in patients’ pelvic lymph nodes. … READ MORE …

Which patients with a PSM post-surgery need early adjuvant therapy?

Could more intensive monitoring of PSA levels in the first few months after a radical prostatectomy help to determine which patients who have a positive surgical margin (PSM) need adjuvant radiation therapy and which don’t? … READ MORE …