New grade group system predicts risk for prostate cancer-specific mortality

According to a report on the Renal & Urology News web site this morning, a new paper about to be published on line in European Urology (by He et al.) has shown that the new ISUP staging system can be used to project risk for prostate cancer-specific mortality, “regardless of treatment received or clinical stage at diagnosis”. … READ MORE …

Predictive accuracy of the new ISUP grading system in a nationwide patient cohort

A paper in European Urology has provided us with additional early data on the applicability of the new ISUP grading system scheduled to replace the Gleason grading system over the next few years. … READ MORE …

Predicting sexual function after first-line treatment for prostate cancer

A newly published report in the Journal of the American Medical Association provides data (from two large cohorts of patients) on the quality of sexual function among men undergoing first-line treatment for localized prostate cancer. … READ MORE …

Risk stratification of men with high-risk prostate cancer prior to first-line surgery

A new French study has attempted to provide a better appreciation of the effect of predictive factors on the biochemical recurrence-free and overall survival of patients with high-risk prostate cancer after a radical prostatectomy (RP). … READ MORE …

The MSKCC-Malmö four-kallikrein model for prediction of prostate cancer risk

The collaborative research between the teams at Memorial Sloan-Kettering Cancer Center in New York and in Malmö in Sweden continues to  refine a model that may allow us to accurately predict which patients are at clinically significant risk for prostate cancer based solely on simple tests run on a single blood sample. … READ MORE …

Projection of 15-year prostate cancer-specific survival after radical prostatectomy

For several years we have been able to use the Kattan nomograms to project 5-, 7-, and 10-year recurrence-free survival before and after radical prostatectomy for localized prostate cancer, based on the patient’s age, stage, Gleason score, and other relevant data (associated with biopsy or surgical findings, as appropriate). … READ MORE …

Psychosocial distress at diagnosis and 12 months later

Every prostate cancer patient (and many patients subsequently found not to have prostate cancer) have been through the psychological and social distress associated with the risk of a diagnosis of prostate cancer. It’s no fun. … READ MORE …