Last week we noted that adding MRI data to the Partin tables and to the Kattan/MSKCC nomograms did not seem to improve the accuracy of prognosis of outcomes after radical prostatectomy. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: biopsy, clinically significant, data, Gleason 7, MRI, outcome, PI-RADS, prediction, PSA, risk | 5 Comments »
According to a report on the Renal & Urology News web site this morning, a new paper about to be published on line in European Urology (by He et al.) has shown that the new ISUP staging system can be used to project risk for prostate cancer-specific mortality, “regardless of treatment received or clinical stage at diagnosis”. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: grade, group, prediction, prognosis, risk, system | 17 Comments »
A paper in European Urology has provided us with additional early data on the applicability of the new ISUP grading system scheduled to replace the Gleason grading system over the next few years. … READ MORE …
Filed under: Diagnosis, Management, Risk | Tagged: grading, ISUP, prediction, risk, system | Leave a comment »
A newly published report in the Journal of the American Medical Association provides data (from two large cohorts of patients) on the quality of sexual function among men undergoing first-line treatment for localized prostate cancer. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Treatment, Uncategorized | Tagged: brachytherapy, external beam radiation therapy, post-treatment, prediction, radical prostatectomy, sexual function | 3 Comments »
A new French study has attempted to provide a better appreciation of the effect of predictive factors on the biochemical recurrence-free and overall survival of patients with high-risk prostate cancer after a radical prostatectomy (RP). … READ MORE …
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: high, outcome, prediction, radical prostatectomy, risk | 4 Comments »
The collaborative research between the teams at Memorial Sloan-Kettering Cancer Center in New York and in Malmö in Sweden continues to refine a model that may allow us to accurately predict which patients are at clinically significant risk for prostate cancer based solely on simple tests run on a single blood sample. … READ MORE …
Filed under: Diagnosis, Risk, Uncategorized | Tagged: biopsy, clinically significant, kallikrein, prediction, PSA, risk | Leave a comment »
For several years we have been able to use the Kattan nomograms to project 5-, 7-, and 10-year recurrence-free survival before and after radical prostatectomy for localized prostate cancer, based on the patient’s age, stage, Gleason score, and other relevant data (associated with biopsy or surgical findings, as appropriate). … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: 15-year, Kattan, mortality, nomogram, PCSM, prediction, projection, prostate cancer-specific, radical prostatectomy, surgery | 38 Comments »
The ability to predict risk for Gleason score upgrading in patients who have any form of treatment other than radical prostatectomy can be important, because it may help treating physicians and their patients to optimize first-line therapy. … READ MORE …
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: Gleanson scvore, prediction, projection, risk, upgrading | Leave a comment »
Patients believed to be at potential risk for prostate cancer that may extend outside the prostate itself — through extracapsular extension (ECE) or seminal vesicle invasion (SVI) — often undergo imaging studies in planning for their treatment. Endorectal coil magnetic resonance imaging (erMRI) as been a commonly used form of such imaging. … READ MORE …
Filed under: Diagnosis, Management | Tagged: accuracy, endorectal, erMRI, extracapsular extension, magetic resonance imaging, MRI, prediction, seminal vesicle invasion | 2 Comments »
A key goal of the prostate cancer research community has been the identification of markers that could help us to better identify patients at high risk for prostate cancer progression as early as possible in the disease process. It now appears that the presence of an enzyme called HYAL-1 hyaluronidase and hyaluronic acid staining in prostatectomy specimens may be able to do this. … READ MORE …
Filed under: Diagnosis, Risk | Tagged: HYAL-1, hyaluronic acid, hyaluronidase, prediction, risk, staining | Leave a comment »
We have separately addressed data from a 15-year follow-up of a population-based Swedish screening study. Other reports today deal with:
Filed under: Management, Prevention, Risk, Treatment | Tagged: anti-androgen, brachytherapy, diet, erectile function, maximal androgen deprivation, monotherapy, potency, prediction, risk, supplement, surgery, zinc | Leave a comment »
Many clinicians and their patients use the so-called Kattan nomograms to help make decisions about outcomes following use of certain types of prostate cancer treatment. Apparently these prediction tools have also become known in at least some circles as “Prostagram” data. (This is the first time The “New” Prostate Cancer InfoLink has ever come across the use of this term.) … READ MORE …
Filed under: Management, Treatment | Tagged: accuracy, actual, correlation, Kattan nomogram, outcome, prediction, Prostagram | 3 Comments »
An Italian group has published an analysis of data from their surgical series suggesting that it is possible to predict the probability of a persistently detectable PSA post-surgery. … READ MORE …
Filed under: Management, Risk | Tagged: detectable PSA, post-surgery, prediction | Leave a comment »
THE "NEW" PROSTATE CANCER INFOLINK 