Rethinking risk stratification for radiation therapy

In 2016, we looked at the Candiolo risk stratification system for radiation therapy. To our knowledge, it has not been prospectively validated or widely adopted. … READ MORE …

Is time to biochemical failure a good surrogate endpoint for overall survival?

For many years researchers have been trying to identify so-called “surrogate” endpoints that can be used to predict overall and prostate cancer-specific survival with high accuracy. … READ MORE …

Projecting the need for confirmatory biopsies in candidates for active surveillance

A newly published paper from the Memorial Sloan-Kettering Cancer Center group in New York has proposed a predictive model which might allow a high percentage of candidates for active surveillance as initial management to skip a second, confirmatory biopsy after initial diagnosis. … READ MORE –