Adverse events of primary, intensity-modulated radiation therapy (IMRT)

In a recent commentary, the Sitemaster mentioned some common adverse effects of radical prostatectomy, some of which (e.g., perceived penile shrinkage, climacturia) are seldom mentioned by urologists to prospective patients, and are not routinely included in standardized quality-of-life questionnaires. … READ MORE …

Primary melanoma of the prostate

Primary melanoma of the prostate is so rare that only five cases of this disorder have ever been reported in the medical literature — and your sitemaster had never even heard of this form of prostate cancer prior to seeing the care report referred to below. … READ MORE …

Modes of biochemical failure after primary radiation therapy may identify aggressive sub-types

The most widely used definition of biochemical failure after primary radiation therapy is the so-called “Phoenix” definition. It’s called that because it was adopted by consensus at a meeting of the American Society for Radiation Oncology (ASTRO) in Phoenix, AZ, in 2005. … READ MORE …

No 15-year survival benefit associated with primary ADT in older men

In another paper just published on-line in JAMA Internal Medicine this week, the authors have provided additional data indicating — once again — the lack of any value of primary androgen deprivation therapy (ADT) in the management of early-stage, localized prostate cancer among older patients. … READ MORE …

Primary ADT ineffective for most men with early stage prostate cancer

Data from a large, retrospective study, reported in the Journal of Clinical Oncology, suggest something that many expert clinicians and patients have long suspected … that early use of androgen deprivation therapy (ADT) alone is not an effective treatment for most men with early stage prostate cancer. … READ MORE …

Debulking the primary tumor in men diagnosed with metastatic prostate cancer

There has long been an unanswered question about the value of “debulking” of the primary tumor in men who are initially diagnosed with advanced forms of prostate cancer — i.e., surgical removal of the prostate or some form of definitive radiation therapy of the primary tumor. … READ MORE …

A rare case of angiosarcoma of the prostate

A recent case report by Humphrey in the Journal of Urology offers information about a 67-year-old patient found to have a form of prostate cancer known as angiosarcoma of the prostate. … READ MORE …