Primary ADT in treatment of elderly men with organ-confined prostate cancer

One really has to wonder whether we are still treating elderly men, initially diagnosed with organ-confined prostate cancer, with first-line or “primary” androgen deprivation therapy ADT)! And if we are, why on Earth is that? … READ MORE …

How primary care physicians could better help prostate cancer patients

A newly published article on the Journal of the American Board of Family Medicine offers some helpful guidance to primary care  physicians on the subject of prostate cancer diagnosis and its management. … READ MORE …

Adverse events of primary, intensity-modulated radiation therapy (IMRT)

In a recent commentary, the Sitemaster mentioned some common adverse effects of radical prostatectomy, some of which (e.g., perceived penile shrinkage, climacturia) are seldom mentioned by urologists to prospective patients, and are not routinely included in standardized quality-of-life questionnaires. … READ MORE …

Primary melanoma of the prostate

Primary melanoma of the prostate is so rare that only five cases of this disorder have ever been reported in the medical literature — and your sitemaster had never even heard of this form of prostate cancer prior to seeing the care report referred to below. … READ MORE …

Modes of biochemical failure after primary radiation therapy may identify aggressive sub-types

The most widely used definition of biochemical failure after primary radiation therapy is the so-called “Phoenix” definition. It’s called that because it was adopted by consensus at a meeting of the American Society for Radiation Oncology (ASTRO) in Phoenix, AZ, in 2005. … READ MORE …

No 15-year survival benefit associated with primary ADT in older men

In another paper just published on-line in JAMA Internal Medicine this week, the authors have provided additional data indicating — once again — the lack of any value of primary androgen deprivation therapy (ADT) in the management of early-stage, localized prostate cancer among older patients. … READ MORE …

Primary ADT ineffective for most men with early stage prostate cancer

Data from a large, retrospective study, reported in the Journal of Clinical Oncology, suggest something that many expert clinicians and patients have long suspected … that early use of androgen deprivation therapy (ADT) alone is not an effective treatment for most men with early stage prostate cancer. … READ MORE …