New data shows that local prostate radiotherapy improves OS in some men with newly diagnosed, metastatic prostate cancer

New data from the ongoing STAMPEDE trial in the UK and Switzerland has now confirmed that ablative radiation of the prostate itself (debulking of the primary tumor) improves overall survival (OS) in men newly diagnosed with metastatic prostate cancer who have a low metastatic disease burden but not in those with higher burden of disease. … READ MORE …

No survival benefit to debulking the prostate with radiation in first randomized clinical trial

The term “debulking” denotes the radical treatment (via prostatectomy or radiation therapy) of the cancerous prostate — lmost always in newly diagnosed patients — after distant metastases have been discovered. … READ MORE …

Does local treatment at time of diagnosis improve outcomes for men initially diagnosed with metastatic disease?

Over the years, a good deal of data has been accumulated suggesting that local treatment (ablation) of the primary tumor may have benefit in the long-term outcomes of men with metastatic prostate cancer at time of initial diagnosis. … READ MORE …

Primary ADT in treatment of elderly men with organ-confined prostate cancer

One really has to wonder whether we are still treating elderly men, initially diagnosed with organ-confined prostate cancer, with first-line or “primary” androgen deprivation therapy ADT)! And if we are, why on Earth is that? … READ MORE …

How primary care physicians could better help prostate cancer patients

A newly published article on the Journal of the American Board of Family Medicine offers some helpful guidance to primary care  physicians on the subject of prostate cancer diagnosis and its management. … READ MORE …

Adverse events of primary, intensity-modulated radiation therapy (IMRT)

In a recent commentary, the Sitemaster mentioned some common adverse effects of radical prostatectomy, some of which (e.g., perceived penile shrinkage, climacturia) are seldom mentioned by urologists to prospective patients, and are not routinely included in standardized quality-of-life questionnaires. … READ MORE …

Primary melanoma of the prostate

Primary melanoma of the prostate is so rare that only five cases of this disorder have ever been reported in the medical literature — and your sitemaster had never even heard of this form of prostate cancer prior to seeing the care report referred to below. … READ MORE …