The clinical significance of high-grade PIN — an update

A newly published mini-review in BJU International deals with the biologic and clinical significance of high-grade prostatic intraepithelial neoplasia (HG-PIN) as a sole finon an initial biopsy for risk of prostate cancer. … READ MORE …

Selenium in treatment of men with HG-PIN to prevent prostate cancer

The SELECT study has previously shown that treatment with selenium did not prevent prostate cancer in your average “guy in the street.” However, what about men with a prior diagnosis of high-grade prostatic intraepithelial neoplasia (HG-PIN)? … READ MORE …

Selenium, vitamin E, soy, and prostate cancer prevention

A new Canadian study just reported in the Journal of Clinical Oncology has failed to find any significant benefit from the use of vitamin E, selenium, and soy protein supplements in the prevention of prostate cancer. … READ MORE …

High-grade PIN and risk for clinically significant prostate cancer: an update

Work by Bostwick and his colleagues (long before the development of Bostwick Laboratories) first showed a clear association between an initial diagnosis of high-grade prostatic intraepithelial neoplasia (HG-PIN) and subsequent risk for a diagnosis of prostate cancer. … READ MORE …

Multifocal, high-grade, prostatic epithelial neoplasia and prostate cancer risk

The presence of high-grade, prostatic epithelial neoplasia (HG-PIN) — in the absence of either prostate cancer or atypia (ASAP) — on an initial biopsy has long been associated with risk for a subsequent diagnosis of cancer. … READ MORE …

The Tuesday news update: March 3, 2009

Today’s news covers:

  • The ongoing trial of toremifene 20 mg in prevention of prostate cancer
  • Interleukin-6 in the development of prostate cancer
  • Preservation of the fascia and recovery of erectile function post-surgery
  • The use of urethral wall stents and delayed artificial urinary sphincters to treat men with severe, recurrent bladder neck contracture and incontinence after radical prostatectomy … READ MORE …