PSA kinetics do not predict pathology in men on active surveillance

The role of PSA kinetics (i.e., PSA doubling time and PSA velocity) in the early diagnosis of prostate cancer and in the monitoring of patients on active surveillance protocols has been controversial. We now have some more definitive data. … READ MORE …

Prostate cancer news reports: Friday, September 18, 2009

In today’s news reports we have focused primarily on data showing that specific things do not seem to work well in prostate cancer risk assessment and diagnosis:

  • Neither PSA velocity nor the PSA/serum testosterone ratio are normally predictive for risk of prostate cancer in undiagnosed patients.
  • Post-surgical tumor volume is not predictive for risk of prostate cancer progression.
  • A new nomogram predicts risk of pathological upgrading post-surgery. … READ MORE …