Can a man be too young for active surveillance?

There is a “conventional wisdom” that active surveillance (AS) is only for older men, and that younger men are better off having immediate radical treatment, typically prostatectomy (RP).

What does “value” mean for prostate cancer patients?

Many readers who weren’t able to join us on yesterday’s CureTalk panel discussion may want to listen to what was a wide-ranging discussion about things that are really valuable to prostate cancers patients at diagnosis and along their prostate cancer journey. … READ MORE …

Improvements in the quality of prostate cancer care (in Australia)

One of the most critical issues for many in the prostate cancer community is whether patients actually receive treatment according to standard guidelines. While getting treatment according to standard guidelines may not imply that a patient is getting the very best possible care, we know that getting treatment according to standard guidelines does at least mean that physicians are seeking to meet or surpass the quality of care that is recommended.

A new paper by Sampurno et al. in the Medical Journal of Australia has provided us with data from the Prostate Cancer Outcomes Registry–Victoria (PCOR-Vic), a state-wide prostate cancer outcomes registry in Victoria (one of Australia’s most highly populated states).

The authors collected and analyzed data on 4,708 men diagnosed with prostate cancer over a 5-year period (from 1 January 2009 and 31 December 2013). The goal was to assess how well prostate cancer care was being delivered when measured against three predefined quality indicators:

  • Alignment with the modified Prostate Cancer Research International Active Surveillance (PRIAS) protocol guideline (QI-1)
  • Timeliness of prostate cancer care for men with high-risk and locally advanced disease (QI-2)
  • The presence of positive surgical margins (PSMs) among men treated surgically for organ-confined, pT2 disease (QI-3)

The entire text of this paper is available on line for interested readers, so we will focus on the “top-line” results of the study, as follows:

  • Over the 5 years of the study there was
    • A downward trend in the percentage of men with low-risk disease who underwent active treatment (from 45 to 34 percent; P = 0.024)
    • An upward trend in the percentage of men with high-risk and locally advanced disease who received active treatment within 12 months of diagnosis (from 88 to 93 percent; P = 0.181)
    • A decline in PSM rate among men with pT2 disease after radical prostatectomy (from 21 to 12 percent; P = 0.036)

The authors note that a limitation of the study is that the improvement in the quality indicators was detected using PCOR-Vic as a single population, but that there could still be institutional variations in quality improvement.

With that reservation, the authors conclude that, over the period 2009 t0 2013

the performance of the Victorian health system improved according to the three processes of care indicators reported by the PCOR-Vic.

The “New” Prostate Cancer InfoLink sees this as an important study because it offers (a) validation of the processes being used in Australia to set and then achieve certain standards of care and (b) a significant set of improvements over 5 years toward achieving such standards of care.

By comparison, in much of America, there are no predefined goal being set by anyone as to levels of acceptable outcomes, nor are there clear educational processes in most states designed to ensure that physicians are seeking to meet or exceed such outcomes.

Longer life or quality of life? What do newly diagnosed patients really want?

A third, and interesting, late-breaking poster to be presented at the upcoming annual meeting of the American Urological Association looked into patient perspectives on quality of life as opposed to quantity of life in prostate cancer treatment decision making. … READ MORE …

A duty of care in the management of prostate cancer

A new article in the journal Nature Reviews: Urology is entitled, “The implications of ageing and life expectancy in prostate cancer treatment.” It’s an important issue. … READ MORE …

Exactly who is doing your radical prostatectomy for you?

According to a newly published article in Urologic Oncology, at least 85 percent of all radical prostatectomies in America are now performed using robot-assisted laparoscopic prostatectomy (RALP). Actually, this is hardly a surprise. However, … READ MORE …

Race, disparities, and end-of-life care for prostate cancer patients

A newly published paper in the Journal of the National Comprehensive Cancer Network has identified a series of significant disparities in there clinical care of African American men as opposed to Caucasians. … READ MORE …