Is race a factor in exercise and prostate cancer prevention?

We have known for some time that regular exercise may lower risk for prostate cancer. Indeed, a study by Clarke and Whittemore published in 2000 suggested that men who take little to no exercise may be 1.7 times more likely to be diagnosed with prostate cancer than those who exercise with a degree of regularity. … READ MORE …

PSA testing has reduced risk for diagnosis with metastatic prostate cancer

A paper published earlier today in Cancer has made a very reasonable attempt to estimate how many men would be being diagnosed annually today with metastatic (TxNxM1) prostate cancer if there was no PSA test and the rates of diagnosis were the same as they were back in the late 1980s — before PSA testing was widely available. … READ MORE …

Do African Americans do worse than Caucasians on active surveillance?

Data to be presented at the annual meeting of the American Society of Clinical Oncology (ASCO) on Sunday, June 3, suggest that African American men with localized prostate cancer may be less likely that Caucasian men to respond well to active surveillance as a management strategy. However, this conclusion comes from a retrospective analysis of data from a relatively small, single-institution case series. … READ MORE …

How am I meant to get THERE from HERE?

A new report just published on line in the Journal of Urology has shown that — at least in the state of North Carolina — distance from the nearest urologist affects prostate cancer risk category at diagnosis and may disproportionately impact black as opposed to white patients. … READ MORE …

African-American men significantly underestimate their risk of a positive prostate biopsy

According to new data from a study at the University of Chicago, African-American males scheduled for a prostate biopsy are at greater risk for a positive diagnosis of cancer than white males and they also significantly underestimate their probability of a positive biopsy result. … READ MORE …

Race and outcomes after prostate brachytherapy

A new retrospective analysis of data from > 2,300 patients suggests that African-American men are a greater risk for biochemical disease recurrence after brachytherapy alone than Hispanics or Caucasian men, but … READ MORE …

Prostate cancer treatment in southwestern Georgia: race and a rural environment

A new study just published in Urology seems to confirm facts that have previously been identified in earlier studies of how men elect to get treated for localized prostate cancer in parts of the USA with a high proportion of African American residents and relatively low income levels. … READ MORE …

48 hours at the IMPaCT symposium in Orlando: Part II

One of the other major initiatives that have been funded over several years by the Department of Defense’s Prostate Cancer Research Program is the North Carolina-Louisiana Prostate Cancer Project (often just known as PCaP). … READ MORE …

Race, patterns of care, and quality of care in the USA

Barocas and Penson have offered a helpful new review of racial variation in the patterns and the quality of care offered to prostate cancer patients in the USA. The entire paper is available on line through the UroToday web site. … READ MORE …

Age, race, interval between tests, and risk for prostate cancer

Unsurprisingly, the longer a man older than 65 years goes between PSA tests, the greater is the likelihood that he will be diagnosed with clinically significant prostate cancer that has escaped from the prostate (especially if he has never had a PSA test until he became Medicare eligiible). … READ MORE …

Prostate cancer news reports: Thursday, January 28, 2010

The news reports today cover studies on:

  • Initial PSA levels and risk for prostate cancer in black and in white Americans
  • 3 T MR imaging, MRI-guided biopsies, and identification of sites of local recurrence after first-line EBRT
  • pT0 disease in men with biopsy-detected prostate cancer
  • Outcomes of immediate surgery compared to deferred treatment … READ MORE …

Prostate cancer news report: Sunday, January 24, 2010

In this weekend’s prostate cancer news reports, we have addressed recent publications on:

  • A SNP that may be specifically linked to risk for prostate cancer in African Americans
  • The need for extended biopsies in men with larger prostates who are considering focal treatment for prostate cancer
  • A possible association between diabetes, race, obesity, and risk for prostate cancer progression
  • Neoadjuvant hormone therapy, brachytherapy, and all cause mortality in older patients … READ MORE …

Socioeconomic status, race, and prostate cancer — the view from California

The differences in risk for and mortality from prostate cancer across racial and ethnic lines have been well documented.However, there has been continuing controversy over the degree to which socioeconomic status (SES) may be able to account for these differences. … READ MORE …

Prostate cancer news reports: Wednesday, May 20, 2009

Today’s news reports address:

  • Prevalence of comorbidities in black and white patients
  • PSA screening and the criteria for biopsy
  • Screening and management of men > 65 years of age
  • Genitourinary toxicity of intensity modulated radiation therapy (IMRT) … READ MORE …

Wednesday’s news reports: February 25, 2009 — Part 1

There has been a positive plethora of news reports over the past 24 hours, starting with the very important issuance of the AUA/ASCO guideline on the potential use of 5-ARIs for the prevention of prostate cancer. This will be just the first of at least three groups of news reports today! This report deals with:

  • A review of the role of IGF-I levels in development (and possible treatment) of prostate cancer
  • The lack of “race-specific” differences in PSA levels based on ancestry
  • An assessment of the feasibility of using genetic variants to test for prostate cancer risk
  • The availability of a research grade (not a clinical) test for sarcosine levels in tissues
  • Interim data on the investigational drug phenoxodiol … READ MORE …