Modes of biochemical failure after primary radiation therapy may identify aggressive sub-types

The most widely used definition of biochemical failure after primary radiation therapy is the so-called “Phoenix” definition. It’s called that because it was adopted by consensus at a meeting of the American Society for Radiation Oncology (ASTRO) in Phoenix, AZ, in 2005. … READ MORE …

Modern 5-year outcome data after radiotherapy for very high-risk patients

A newly published paper reports 5-year outcome data from a series of men initially diagnosed with very high-risk, but localized prostate cancer — all of whom were treated with either dose-escalated external beam radiation therapy (EBRT) or pelvic radiation + permanent interstitial seed implantation (combined modality radiotherapy or CMRT). … READ MORE …

5-year cumulative incidence of complications after surgery or radiation therapy

A new report just published in Lancet Oncology provides data on complications other than incontinence and erectile dysfunction (ED) after surgical or radiotherapeutic treatment of prostate cancer within 5 years of the initial treatment. … READ MORE …

AUA, ASTRO issue new guidance on radiation after radical prostatectomy

So the American Urology Association (AUA) is clearly “on a roll” when it comes to guidance on the detection and management of prostate cancer. This is the third new guidance document issued in a matter of days. … READ MORE …

Salvage ADT after failure of radiation therapy — the art of good timing

The art of good timing and good patient selection is important to the appropriate use of salvage hormone therapy in all men who are in biochemical failure after first- or second-line radiation therapy. A study published in “the Red Journal” helps to make this point. … READ MORE …

PBRT vs. IMRT — are we about to get the definitive trial?

According to an article in the Boston Globe this morning, we are (supposedly and finally) going to get the study needed to try to demonstrate whether there is a real clinical benefit to proton beam radiation therapy as compared to modern, intensity-modulated radiation therapy in men with localized prostate cancer! … READ MORE …

PBRT and prostate cancer: your breakfast read on Bloomberg.com

Ye of faith … and ye of rather less faith … in the merits of proton beam radiation therapy (PBRT) compared to other forms of treatment for management of localized prostate cancer may want to read through Robert Langreth’s article (“Prostate cancer therapy too good to be true explodes health cost“) posted this morning on the Bloomberg.com web site. … READ MORE …