The most widely used definition of biochemical failure after primary radiation therapy is the so-called “Phoenix” definition. It’s called that because it was adopted by consensus at a meeting of the American Society for Radiation Oncology (ASTRO) in Phoenix, AZ, in 2005. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical, failure, primary, radiation therapy | 3 Comments »
A newly published paper reports 5-year outcome data from a series of men initially diagnosed with very high-risk, but localized prostate cancer — all of whom were treated with either dose-escalated external beam radiation therapy (EBRT) or pelvic radiation + permanent interstitial seed implantation (combined modality radiotherapy or CMRT). … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: "high risk", outcome, radiation therapy, very | 3 Comments »
A new report just published in Lancet Oncology provides data on complications other than incontinence and erectile dysfunction (ED) after surgical or radiotherapeutic treatment of prostate cancer within 5 years of the initial treatment. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: complications, hospitalization, radiation therapy, surgery | 16 Comments »
So the American Urology Association (AUA) is clearly “on a roll” when it comes to guidance on the detection and management of prostate cancer. This is the third new guidance document issued in a matter of days. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment, Uncategorized | Tagged: adjuvant, guideline, radiation therapy, radical prostatectomy, salvage | 4 Comments »
The art of good timing and good patient selection is important to the appropriate use of salvage hormone therapy in all men who are in biochemical failure after first- or second-line radiation therapy. A study published in “the Red Journal” helps to make this point. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen deprivation, radiation therapy, salvage, survival | 11 Comments »
According to an article in the Boston Globe this morning, we are (supposedly and finally) going to get the study needed to try to demonstrate whether there is a real clinical benefit to proton beam radiation therapy as compared to modern, intensity-modulated radiation therapy in men with localized prostate cancer! … READ MORE …
Filed under: Management, Treatment | Tagged: IMRT, PBRT, photon, proton, radiation therapy | 2 Comments »
Ye of faith … and ye of rather less faith … in the merits of proton beam radiation therapy (PBRT) compared to other forms of treatment for management of localized prostate cancer may want to read through Robert Langreth’s article (“Prostate cancer therapy too good to be true explodes health cost“) posted this morning on the Bloomberg.com web site. … READ MORE …
Filed under: Management, Treatment | Tagged: cost, PBRT, proton beam, radiation therapy, value | 13 Comments »
A new review published recently in the British Journal of Cancer addresses appropriate current practice regarding the use of neoadjuvant and adjuvant androgen deprivation therapy (ADT) in combination with radiation therapy in the management of patients with high-risk localized and locally advanced forms of prostate cancer. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: "high risk", ADT, androgen deprivation, localized, locally advanced, outcomes, radiation therapy, survival | 11 Comments »
According to an announcement from the European Association for Urology (EAU) earlier today, data from a recently completed trial demonstrate that degarelix is “non-inferior” to the LHRH agonist goserelin acetate + the antiandrogen bicalutamide at reducing prostate volume in men with advanced hormone- dependent prostate cancer. … READ MORE …
Filed under: Diagnosis, Drugs in development, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: adjuvant, Degarelix, neoadjuvant, radiation therapy | 2 Comments »
For the first time, some 15 years after proton beam radiation therapy (PBRT) was initially popularized as a potential treatment for prostate cancer by the group at Loma Linda, we have an independent assessment of the risk for side effects associated with this form of radiation therapy … and the comparative data are not good. … READ MORE …
Filed under: Management, Treatment | Tagged: IMRT, outcome, proton beam, radiation therapy, safety | 8 Comments »
The issue of whether some urology practices are investing in equipment capable of delivering intensity-modulated radiation therapy (IMRT) with financial motives is back on the front burner again. … READ MORE …
Filed under: Uncategorized | Tagged: IMRT, motive, profit, radiation therapy, self-referral | 4 Comments »
A media release issued yesterday by ASTRO reads as follows: … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: brachytherapy, efficacy, outcome, PBRT, proton beam, radiation therapy, safety | 5 Comments »
A new article in the journal Anticancer Research suggests that patients had greater satisfaction after modern forms of external beam radiation therapy (EBRT) than after some other standard forms of first-line treatment. Of course the absolute truth of this conclusion may be affected by the details of the study. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: brachytherapy, external beam, hormone therapy, outcome, patient, radiation therapy, satisfaction, surgery | 1 Comment »
The use of second-line radiation therapy following biochemical progression after first-line radiation therapy for localized forms of prostate cancer has long been limited by concerns about tolerance for rectal and related radiation toxicities. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: radiation therapy, re-irradiation, second-line | 3 Comments »
Two recent papers have reported data relevant to the application of high-dose, image-guided, intensity-modulated forms of radiation therapy (IGRT/IMRT) in the first-line treatment of men with localized prostate cancer. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: IGRT, image-guided, IMRT, intensity-modulated, radiation therapy, side effects, toxicity | 2 Comments »
