Data from a recently published, Canadian, clinical trial of high-dose vitamin D as a method to strengthen bones in healthy adults who do not have osteoporesis have had significant and unexpectedly negative results. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: dose, high, outcome, randomized, trial, vitamin D | 18 Comments »
In the first trial ever to randomly assign patients to extreme hypofractionation, primary radiation therapy delivered in just seven treatments had the same effectiveness and safety as 39 treatments. … READ MORE …
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: 3D-CRT, body, conventional, outcome, radiation, randomized, SBRT, stereotactic, trial | 2 Comments »
Back in July we reported the initial publication on line of the results of a randomized Phase III trial by Yaxley et al. that compared the initial outcomes of open radical retropubic prostatectomy to robot-assisted laparoscopic prostatectomy (RALP). This paper has now been published by The Lancet along with two sets of editorial commentary. … READ MORE …
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: open, outcome, RALP, randomized, surgery, trial | Leave a comment »
When you go to large meetings with thousands of presentations, you miss things. And here’s one that a lot of people seem to have missed — your sitemaster included. … READ MORE …
Filed under: Uncategorized | Tagged: IMRT, lung, PBRT, proton, randomized, trial | 1 Comment »
So TOAD stands for “Timing of Androgen Deprivation” and refers to a randomized, multi-center, Phase III trial carried out in Australia, New Zealand, and Canada between September 3, 2004, and July 13, 2012. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, delayed, deprivation, immediate, randomized, trial | 3 Comments »
Data from a randomized clinical trial have shown that there is more than one way to reduce the size of a man’s prostate (if such cytoreduction is needed) prior to treatment with permanent, radioactive pellets (permanent, low-dose brachytherapy) for localized prostate cancer. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Treatment | Tagged: bicalutamide, brachytherapy, cytoreduction, dutasteride, randomized, trial | 6 Comments »
We should emphasize immediately that the available data from the trial discussed below are not exactly compelling. For whatever reasons, the trial didn’t enroll enough patients to allow any conclusions about the relative effectiveness to the two forms of treatment. … READ MORE …
Filed under: Management, Treatment | Tagged: radiation, randomized, surgery, trial | 1 Comment »
Over the years, it has proved almost impossible to recruit patients to comparative trials of different types of first-line treatment in the management of localized prostate cancer — particularly in the USA. … READ MORE …
Filed under: Diagnosis, Management, Treatment, Uncategorized | Tagged: first line, localized, randomized, registry, SABRE1, trial | 6 Comments »
For the first time ever — as far as anyone seems to be aware — a major cancer center will soon start to implement a controlled, randomized clinical trial of calorie restriction as a treatment for cancer. And they will be doing this trial in men with progressive prostate cancer. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: calorie, diet, randomized, restriction, trial | 8 Comments »
A new study just published in The Lancet has reported that — among men who have urinary incontinence 6 weeks after a radical prostatectomy (RP) — formal one-on-one training of patients by expert therapists does not in fact reduce the rate of continence at 12 months compared to patients in a control group. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: continence, exercises, incontinence, Kegel, outcome, radical prostatectomy, randomized, training, trial | 4 Comments »
It has been suspected for many years that intermittent androgen deprivation (ADT) might have the same or a better impact on survival of prostate cancer patients as continuous ADT, with potentially superior effects on other factors such as quality of life. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen deprivation therapy, continuous, intermittent, randomized | 2 Comments »
A newly published Italian study offers what we believe to be the first direct comparison of two “modern” types of external beam radiation therapy for the treatment of localized, high-risk prostate cancer. This is a relatively small trial, with relatively brief follow-up to date, but the results are nontheless interesting and important. … READ MORE …
Filed under: Management, Treatment | Tagged: "high risk", external beam radiation, localized, randomized, trial | 2 Comments »
Earlier this year we reported the initial results of a truly randomized Canadian trial of cryotherapy vs. external beam radiation therapy (EBRT) for the treatment of localized prostate cancer. The same group of authors have now reported follow-up data on quality of life. … READ MORE …
Filed under: Management, Treatment | Tagged: cryoablation, cryotherapy, EBRT, external beam radiation therapy, randomized, trial | 2 Comments »
Bill-Axelson et al. have just published an update of the Scandinavian Prostate Cancer Research Group’s prospective, randomized trial of watchful waiting vs. radical prostatectomy. The most recent results are somewhat worrisome.
For a detailed update on this study, please read the article entitled “Watchful waiting vs. radical surgery: the Scandinavian trial” elsewhere on this site. However, the crucial information is that at 10.8 years of follow-up there appears to have been no increase in the overall or the disease-specific survival benefit compared to the data at 8.2 years of follow-up.
Filed under: Management, Treatment | Tagged: cancer, news, prostate, prostatectomy, radical, randomized, Scandinavian, trial, waiting, watchful | 3 Comments »
THE "NEW" PROSTATE CANCER INFOLINK 