INO-5150 in early treatment of biochemically recurrent prostate cancer

In 2015, Inovio Pharmaceuticals started a Phase I trial of INO-5150 — a new type of immunotherapy using a DNA vaccine for prostate cancer which targets both prostate-specific antigen (PSA) and prostate-specific membrane antigen (PSMA). … READ MORE …

Gallium-68 PSMA PET/CT scans changed management in 39 percent of patients

The gold standard for the clinical relevance of any new test in the management of a specific disease is … Do the results of the test change the way a physician would previously have managed patients? … READ MORE …

Radio-guided salvage surgery for recurrent prostate cancer

A recent article (in German in Der Urologe) has discussed the early use of PSMA-radio-guided surgery (PSMA-RGS) for targeted resection of localized prostate cancer recurrence. … READ MORE …

Physical activity and cancer recurrence: a detailed review

Readers with a strong interest in the relationships between exercise and risk for cancer recurrence may want to download and read the full text of a recent article by Friedenreich et al. … READ MORE …

What we have learned from radiolabeled choline PET/CT scanning to date

A newly published paper in the Journal of Urology provides additional data on the role of sophisticated, modern scanning methods in the management of men with recurrent prostate cancer after first-line surgical treatment. … READ MORE …

Is IL-33 expression a key to risk for prostate cancer progression and metastasis?

According to a newly published article in the journal Scientific Reports, men who lose normal expression of a protein known as interleukin-33 or IL-33 are at higher risk for recurrence of their prostate cancer within 5 years than men who do not lose the expression of this biomarker. … READ MORE …

Co-morbidity, outcome, all-cause survival, biochemical recurrence, and additional treatment

So we have all heard the commonly used phrase that men with diagnosed with prostate cancer are “more likely to die with prostate cancer than of it” — and there is certainly truth to this generalization. … READ MORE …