The APCCC in Basel, Switzerland: Day 1

So in this series of reports on what happened at the 3rd Advanced Prostate Cancer Consensus Conference (APCCC) in Basel, Switzerland, we will not be trying to get into detail about exactly what data got presented each day. … READ MORE …

Radio-guided surgery in the treatment of recurrent, initially localized prostate cancer

The re-treatment of patients with recurrent prostate cancer after initial, first-line treatment for what was initially diagnosed as localized disease can be complicated. Success (i.e., effective re-treatment with curative intent) in the re-treatment of such patients is often dependent on the ability to identify exactly where recurrence has occurred. … READ MORE …

ADT + bevacizumab as first-line treatment of recurrent prostate cancer

Data from a small, randomized, Phase II, clinical trial have suggested a possible role for bevacizumab (Avastin) in the treatment of men with recurrent prostate cancer along with androgen deprivation therapy (ADT). … READ MORE …

White button mushroom powder and recurrent prostate cancer

A small Phase I clinical trial in just 36 patients, funded by the Mushroom Growers of Australia and North America, has suggested that powdered mushroom may have an effect on PSA levels of at least some men with recurrent prostate cancer after first-line therapy. … READ MORE …

Gallium-68 PSMA as an imaging agent in prostate cancer recurrence

A report in the Journal of Nuclear Medicine suggests that gallium-68 PSMA (68Ga-PSMA or [68Ga]PSMA) is better than an older radionuclide in detecting recurrent lesions in men with progressive prostate cancer after first-line therapy with surgery or radiation therapy. … READ MORE …

INO-5150 enters initial clinical trials

Inovio Pharmaceuticals is initiating a Phase I trial of INO-5150 — a new type of immunotherapy for prostate cancer which targets both the prostate-specific antigen (PSA) and the and the prostate specific membrane antigen (PSMA). … READ MORE …

Salvage treatment of recurrent, lymph node-positive prostate cancer in the modern era

The advent of imaging tests like the [11C]choline PET/CT scan and others have made it possible to identify, relatively early, the presence of one or more foci of recurrent prostate cancer after first-line therapy, and often these recurrent foci can be found in patients’ pelvic lymph nodes. … READ MORE …