Yes, you are at risk … but risk of exactly what?

An article just published in Urologic Oncology has reported — perhaps not surprisingly — that men who have a single, initial negative biopsy as a consequence of suspicion of prostate cancer are at significant risk for actual diagnosis of prostate cancer over the next 20 years. … READ MORE …

Howard Wolinsky dodges another MRI and another biopsy

Under the heading “Rats, my PSA went up. Do I need another bleeping biopsy?” Howard Wolinsky provides us with the latest “lowdown” on his 8-year-long prostate cancer journey on active surveillance. … READ MORE …

“I’m not having another biopsy after the last one!”

It will come as no particular surprise that men who have had complications after a prior biopsy tend to be less enthusiastic when it is suggested that they need another one. However, … … READ MORE …

Repeated treatment with radium-223 after a first treatment cycle

Radium-223 or Xofigo was first approved in 2013 as “an alpha particle-emitting radioactive therapeutic agent indicated for the treatment of patients with castration-resistant prostate cancer, symptomatic bone metastases and no known visceral metastatic disease.” That meant (and still means) one course of treatment with six cycles of radium-223. However, … READ MORE …

mpMRIs vs. biopsies for repeat evaluations on active surveillance

A question on the minds of many prostate cancer researchers and clinicians (not to mention their patients) is if and when we may be able to replace repeat systematic prostate biopsies for patients on active surveillance (or seeking to start on active surveillance) with the significantly less invasive multiparametric MRIs (mpMRIs). … READ MORE …

Getting a repeat PSA test prior to biopsy … value now confirmed

For quite a while now The “New” Prostate Cancer InfoLink and many others have been advising men who get a single, somewhat elevated PSA test result to get that test repeated before they make any decisions about what else they may need to do. … READ MORE …

Low-dose salvage brachytherapy after first-line EBRT

The potential to use some form of second-line radiation therapy after failure of first-line radiation therapy has long been intriguing, and is highly dependent on the dose and precise volume of the target of first-line radiation therapy. … READ MORE …

Morbidity associated with HIFU at three UK academic centers

A group of three centers in the UK has been investigating the appropriate use of high-intensity focused ultrasound (HIFU) since 2004. … READ MORE …

Understanding new tests for risk of clinically significant prostate cancer

Over the next few years we are going to see the development and marketing of a plethora of new tests related to the diagnosis and prognosis of prostate cancer. Some of these tests may have high utility and value. Others are likely to have a much lower value (but still see high use). As an example, let’s look at the (relatively new) Confirm MDx for Prostate Cancer test. … READ MORE …

Should all low-risk prostate cancer patients be re-biopsied prior to implementation of active surveillance?

Centers apply a variety of inclusion criteria in evaluating the eligibility of patients for management using active surveillance (AS) protocols. The applicability of an immediate, transrectal ultrasound (TRUS)-guided re-biopsy is recommended by a number of centers, but there is no consensus about the need for re-biopsy at this time. … READ MORE …

Prostate cancer news reports: Saturday, June 20, 2009

Today’s news reports cover just two recent review articles, on:

  • Current indications for repeat biopsy
  • MRI, CT, and PET scanning in prostate cancer patients with biochemical progression after first line therapy … READ MORE …