Geographic risk for advanced and metastatic prostate cancer

New research data on the epidemiology of advanced prostate cancer here in the US has confirmed something that has long been understood (albeit not previously as well documented). … READ MORE …

Evidence for dose escalation in adjuvant/salvage radiation

It is well known that prostate cancer is relatively radio-resistant compared to other kinds of cancer. … READ MORE …

Decision aids and prostate cancer: how useful are they?

Your sitemaster has long had concerns about the real value of decision aids in helping men to think about and come to conclusions about controversial issues in the diagnosis and management of prostate cancer. … READ MORE …

AS in practice in a specific US community setting

In a presentation at the ASCO annual meeting, Dr. Ronald Chen reported that just 32 percent of newly diagnosed men who were initially managed on active surveillance (AS) in North Carolina between 2011 and 2013 were actually managed in compliance with guideline recommended monitoring. … READ MORE …

BPH, 5-ARIs, PSA, and risk for prostate cancer diagnosis

It will come as no surprise to the well-informed that if you are taking a 5-alpha-reductase inhibitor (a 5-ARI) like dutasteride or finasteride for benign prostatic hyperplasia (BPH), it significantly lowers your “normal” PSA level (to about half the actual value). … READ MORE …

Ploidy status and risk for prostate cancer-specific mortality

We have known for many years (certainly at least 20) that the presence of abnormal numbers of chromosomes (aneuploidy) in prostate cancer tumor cells is a risk factor for more serious forms of prostate cancer. … READ MORE …

No association between alcohol consumption and lethal prostate cancer

A newly published article in the Journal of Clinical Oncology has again confirmed that there seems to be no really meaningful association between moderate alcohol consumption and risk for lethal prostate cancer. … READ MORE …