PCA3, mpMRI, targeted biopsies, and risk for diagnosis of prostate cancer

The degree to which the PCA3 test is a useful tool in assessment of risk for clinically significant prostate cancer prior to biopsy has never, really, been entirely clear. … READ MORE …

Obesity and risk for diagnosis with prostate cancer

A new report from the International Agency Research on Cancer (IARC) Handbook Working Group has concluded that there is a definitive link between “body fatness”  and increased risk for diagnosis with 13 different types of cancer — but prostate cancer is not on that list. … READ MORE …

The impact of the USPSTF recommendation against screening: another take

A research letter from the epidemiologists and statisticians at the American Cancer Society has just been published in JAMA Oncology. The full text of the research letter is available on line. … READ MORE …

“Why gene tests for cancer don’t offer more answers”

An article with the above title appears to be scheduled for upcoming publication in Scientific American but is already available on line on the Scientific American web site. It may be of interest to a number of our readers. … READ MORE …

Selenium rising … all over again

As some of our older readers will remember, there was a major Phase III clinical trial several years ago (the SELECT trial) designed to study whether taking regular selenium supplements could help to lower risk for a diagnosis of prostate cancer. It didn’t. … READ MORE …

Is ADT giving you Alzheimer’s disease? … Another look

Late last year we reported on a study in the Journal of Clinical Oncology that suggested the possibility of a link between androgen deprivation therapy (ADT) and the onset of Alzheimer’s disease. … READ MORE …

Prevalence of DNA-repair germline mutations in men with metastatic prostate cancer

A new study in this week’s New England Journal of Medicine reports that DNA-repair germline mutations were found in nearly 12 percent of patients who had metastatic prostate cancer. … READ MORE …

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