Aggressive, neoadjuvant androgen ablation prior to surgery in higher risk prostate cancer patients

The development of drugs like abiraterone acetate and enzalutamide has stimulated new research into the use of such agents early on, in combination with first-line therapy, to see if it can affect the outcomes for men with high-risk and unfavorable intermediate-risk prostate cancer. … READ MORE …

Genetics, PSA, and steps toward a better prostate cancer risk management strategy

A new analysis of a large data set compiled by Kaiser Permanente suggests that combining PSA data with genetic risk data may offer a much more effective way to assess risk for clinically significant prostate cancer. … READ MORE …

Risk, prostate cancer, and being 70 to 80 years of age

So a relatively new article in Reviews in Urology caught your Sitemaster’s eye this morning — and worried him because it seemed to be communicating a conclusion of questionable accuracy, which we will explore below. And if we have misinterpreted the data provide in the paper, we are more than willing to be corrected. … READ MORE …

USPSTF selects AUA-nominated urologist to review evidence report on prostate cancer screening

As many readers will be aware, the U.S. Preventive Services Task Force (USPSTF) is in process of developing a new “evidence report” which will form the basis of any update to current USPSTF recommendations about prostate cancer screening. … READ MORE …

The impact of emotional distress on prostate cancer decision-making

According to a newly published paper in the Journal of Urology,

Emotional distress may motivate men with low risk prostate cancer to choose more aggressive treatment. Addressing emotional distress before and during treatment decision making may reduce a barrier to the uptake of active surveillance.

… READ MORE

Another research team, and another micro-RNA …

Last week we mentioned that one specific form of micro-ribonucleic acid (miRNA) may be usable in the development of a drug or drugs to stop the process of metastasis in men with high-risk forms of prostate cancer. Another recent study goes one step further than that. … READ MORE …

Are you going bald? Here’s an update on your prostate cancer risk

It has been suspected for years that there was some form of connection between “male pattern baldness” and being at risk for prostate cancer, and past studies have tended to validate this, but arguably not as well as the one described below. … READ MORE …