Albertsen on the problems of screening and active surveillance

A paper just published in European Urology addresses pathologic outcomes among men initially managed with active surveillance and subsequently treated by deferred radical prostatectomy (RP). The paper stimulated an important set of editorial comments by Albertsen, which we strongly recommend to readers (along with the response from the authors of the original paper). … READ MORE …

Delaying surgery for localized prostate cancer … what’s the downside?

A paper published in June this year in the Journal of Sexual Medicine suggests that delaying radical prostatectomy (RP) as a first-line treatment for localized prostate cancer has no significant effects on post-surgical pathology or mortality but may lead to higher risk for incontinence and erectile dysfunction. … READ MORE …

Comparative data on open and robot-assisted prostatectomy in “low caseload” facilities

A newly reported Swiss study provides us with what appear to be some sound comparative data on the relative merits of open radical prostatectomy (RP) and robot-assisted radical prostatectomy (RALP) at a center with a relatively low-volume caseload. … READ MORE …

Clinical implications of an initial diagnosis of ASAP

Relatively few data have been published on the pathological outcomes of patients initially diagnosed with atypical small acinar proliferation (ASAP), i.e., atypical glands suspicious but not diagnostic for prostate cancer, who are diagnosed with prostate cancer on re-biopsy and then treated by radical prostatectomy. … READ MORE …

Quality of life after first-line treatment: a prospective, comparative study

Data to be published in the May 2010 issue of the Journal of Urology are going to make a lot of urologists rather less than happy about the implications for the use of radical prostatectomy as first-line treatment for prostate cancer. … READ MORE …

Surgery for lymph node-positive prostate cancer: a second look

For many years, the urology group at the Mayo Clinic has argued that surgery is a viable form of treatment for at least some patients with TxN+M0 prostate cancer. A retrospective analysis of data from the Munich Cancer Registry in Germany now seems to confirm this argument. … READ MORE …

Chronic fatigue after first-line therapy for localized prostate cancer

There are few good data on the occurrence of chronic fatigue after first-line treatment of localized prostate cancer. … READ MORE …