Selenium rising … all over again

As some of our older readers will remember, there was a major Phase III clinical trial several years ago (the SELECT trial) designed to study whether taking regular selenium supplements could help to lower risk for a diagnosis of prostate cancer. It didn’t. … READ MORE …

Lycopene, selenium, GTCs, and (maybe?) the prevention of prostate cancer — or maybe not

There have really been very few meaningful, randomized, double-blind trials of any forms of supplement in the prevention of prostate cancer … and to date none of the trials that have been done have shown unarguably meaningful, positive results. … READ MORE …

Time for men to stop taking OTC vitamin E and selenium supplements

According to a media release issued by the Fred Hutchinson Cancer Research Center late last Friday, “high-dose supplementation with both the trace element selenium and vitamin E increase the risk of high-grade prostate cancer.  But importantly, this risk depends upon a man’s selenium status before taking the supplements.” … READ MORE …

Selenium levels in tissue and prostate cancer risk

According to a paper presented yesterday by Geybels et al. at the ongoing annual meeting of the American Association for Cancer Research in Washington, DC, among almost 60,000 men aged 55 to 69 at the beginning of the study, the men with the highest levels of selenium in their toenail clippings were 60 percent less likely to develop advanced prostate cancer. … READ MORE …

Back to the question of whether selenium levels affect prostate cancer risk

A newly published review and meta-analysis in The American Journal of Clinical Nutrition has suggested that biological levels of selenium that fall outside a relatively narrow “normal” range may well be associated with increased risk for prostate cancer. … READ MORE …

Selenium in treatment of men with HG-PIN to prevent prostate cancer

The SELECT study has previously shown that treatment with selenium did not prevent prostate cancer in your average “guy in the street.” However, what about men with a prior diagnosis of high-grade prostatic intraepithelial neoplasia (HG-PIN)? … READ MORE …

Selenium, vitamin E, soy, and prostate cancer prevention

A new Canadian study just reported in the Journal of Clinical Oncology has failed to find any significant benefit from the use of vitamin E, selenium, and soy protein supplements in the prevention of prostate cancer. … READ MORE …