We have long been bedeviled by questions about some of the short- and the long-term side effects and complications of androgen deprivation therapy (ADT) in the treatment of prostate cancer. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, Alzheimer's, androgen, dementia, deprivation, failure, heart, side effect | 2 Comments »
A few days ago we commented briefly on a paper by Haque et al. on the risk for cardiovascular complications and side effects of ADT in men initially diagnosed with localized prostate cancer and supposedly managed, initially, on active surveillance. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: ADT, androgen, cardiovascular, deprivation, side effect | 1 Comment »
In a commentary a couple of days ago we noted some diversity among medical opinion leaders about the safety of treatment with statins. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: mortality, risk, side effect, statin, Treatment | 2 Comments »
In addition to the French data previously referred to on this site, data from another, much larger cohort of men treated with focal, high-intensity focused ultrasound (focal HIFU) are also to be presented at the upcoming annual meeting of the American Urological Association. … READ MORE …
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: focal, hemiablation, HIFU, intermediate risk, outcome, side effect | 4 Comments »
A Dutch research group has published the toxicity outcomes of a randomized clinical trial (HYPRO) designed to test whether a hypofractionated external beam (EBRT) regimen compared to conventional fractionation. They will report on the oncological outcomes at a later date. … READ MORE …
Filed under: Living with Prostate Cancer, Treatment | Tagged: "high risk", fractionation, hypofactionated, intermediate risk, outcome, radiation, side effect | 5 Comments »
For several years now, the Ahmed/Emberton-led research team in the United Kingdom (UK) has published the majority of the detailed outcomes data from treatment of men with localized prostate cancer using high-intensity focused ultrasound (HIFU). This group has now given us 5-year outcomes on a cohort of > 550 patients. … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: complication, focused, HIFU, high-intensity, outcome, side effect, ultrasound | 13 Comments »
Today’s news contained items that run the spectrum from the clinical value of tomatoes and lycopene via the cardiovascular side effects of LHRH agonists and antagonists to the question of whether proton beam radiation therapy is really cost-effective. So here are the “news shorts” for the day: … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Prevention, Risk, Treatment | Tagged: agonist, antagonist, cost-effectiveness, LHRH, lycopene, proton beam, PSA density, side effect, testosterone, tomato | 3 Comments »
Reducing the number of radiation treatments but giving a slightly higher dose of radiation at each visit (“hypofractionation”) had no long-term differential effect on patients’ urinary, rectal, or sexual quality of life, … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: hypofractionation, outcome, quality of life, radiation, side effect | 3 Comments »
Some recent randomized clinical trials have shown that adding androgen deprivation therapy (ADT) to radiation therapy can improve outcomes in some circumstances. However, … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: ADT, androgen deprivation, cardiovascular, radiation, risk, side effect | 2 Comments »
There are many details of stereotactic body radiation therapy (SBRT) that may be optimized over the coming years. Among them is the optimum treatment schedule — i.e., how far apart should the treatments be spaced? … READ MORE …
Filed under: Management, Treatment | Tagged: body, radiation, SBRT, side effect, stereotactic, toxicity | Leave a comment »
Data from a study conducted by a research team at Fox Chase Cancer Center here in Philadelphia may be able, in time, to help to identify when and how much various prostate cancer treatments will impact urinary and sexual functioning. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: erectile, function, sexual, side effect, urinary | Leave a comment »
Denosumab — marketed as Xgeva and as Prolia — is associated with a rare but well-known risk for severe hypocalcemia (very low calcium in the blood stream). Denosumab, when give as Xgeva, is specifically indicated for the prevention of skeletal-related events in patients with bone metastases from prostate and other forms of cancer. … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: denosumab, hypocalcemia, risk, side effect, vitamin D | 1 Comment »
A new paper, published online today in the Journal of Clinical Oncology, suggests that stereotactic body radiation therapy (SBRT, commonly delivered using the CyberKnife system) has a higher risk for genitourinary (GU) toxicity than intensity-modulated radiation therapy (IMRT). … READ MORE …
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: radiation, risk, SBRT, side effect, stereotactic, toxicity | 10 Comments »
We have already mentioned the article on genomics and biomarkers in this month’s issue of AUA News, but there are two other articles in this issue of the publication that are likely to be of interest to at least some of our regular readers. … READ MORE …
Filed under: Living with Prostate Cancer | Tagged: dysfunction, erectile, incontinence, prostatectomy, sexual, side effect, surgery | Leave a comment »
THE "NEW" PROSTATE CANCER INFOLINK 