Posted on October 3, 2014 by Sitemaster
An article just published on line in Clinical Cancer Research supposedly reports the discovery of a single nucleotide polymorphism or SNP that may be useful in predicting which patients with Gleason 7 disease are most likely to have a more aggressive form of cancer. … READ MORE …
Filed under: Diagnosis, Management, Risk | Tagged: aggressiveness, biomarker, Gleason, grade, KLK3, nucleotide, polymorphism, single, SNP | 1 Comment »
Posted on August 19, 2011 by Sitemaster
We lost count some time ago of the number of different single nucleotide polymorphism (SNPs) that had been “associated” in some way or other with risk for prostate cancer and/or with risk for more aggressive forms of prostate cancer in specific sets of people (e.g., Swedes, African-Americans, Ghanaians, Caucasians in general, you name it). … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: gene, prognosis, risk, single nucleotide polymorphism, SNP | 1 Comment »
Posted on April 18, 2011 by Sitemaster
Under the “And this helps me how?” column we can now add the topic of a possible genetic link between endometrial cancer and prostate cancer (maybe). … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Risk | Tagged: cancer, endometrial, genome, SNP, womb | Leave a comment »
Posted on March 29, 2011 by Sitemaster
Previous research using so-called “genome-wide association studies” or GWAS have suggested that there may be as many as 30 different inherited prostate cancer genetic risk variants. What we don’t know much about yet is the relationships between specific genetic risk variants and the clinical outcomes of patients carrying those variants. … READ MORE …
Filed under: Diagnosis, Management, Risk | Tagged: genetics, outcome, risk, SNP, variant | 5 Comments »
Posted on August 2, 2010 by Sitemaster
A large study of genetic markers in Japanese prostate cancer patients has clearly shown that some of the markers of prostate cancer in Caucasians do not appear in Japanese patients whereas new markers appear to be common among Japanese. … READ MORE …
Filed under: Diagnosis, Risk | Tagged: association, genetics, genome, SNP | Leave a comment »
Posted on January 24, 2010 by Sitemaster
In this weekend’s prostate cancer news reports, we have addressed recent publications on:
- A SNP that may be specifically linked to risk for prostate cancer in African Americans
- The need for extended biopsies in men with larger prostates who are considering focal treatment for prostate cancer
- A possible association between diabetes, race, obesity, and risk for prostate cancer progression
- Neoadjuvant hormone therapy, brachytherapy, and all cause mortality in older patients … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: African American, age, biopsy, brachytherapy, diabetes, focal, hormone therapy, mortality, neoadjuvant, obesity, race, single nucleotide polymorphism, SNP, Treatment | Leave a comment »
Posted on September 21, 2009 by Sitemaster
Two new papers published on line in Nature Genetics have added a total of nine more genetic variants to the number of variants associated with an increased risk for prostate cancer. … READ MORE …
Filed under: Diagnosis, Risk | Tagged: DNA, genetics, SNP, variant | Leave a comment »
Posted on July 7, 2009 by Sitemaster
In today’s news reports we address new data on:
- The possible association between PSA levels and SNPs
- Patient age at diagnosis and prostate cancer outcomes
- Revalidation of the Stephenson nomogram for outcomes after salvage radiation therapy
- Failure to follow best practices for radiation of bony metastases … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment, Uncategorized | Tagged: age, best practices, Diagnosis, external beam radiation, nomogram, PSA, salvage, single nucleotide polymorphism, SNP | Leave a comment »
Posted on April 24, 2009 by Sitemaster
In today’s news report we touch on papers that address:
- Genome studies and identification of real genomic risk for prostate cancer
- More on the potential of 5-ARIs in prevention of prostate cancer
- Whether we really need more studies on selenium as a potential prostate cancer prevention agent
- The evolving potential of targeted focal therapy … READ MORE …
Filed under: Living with Prostate Cancer, Management, Prevention, Risk, Treatment | Tagged: 5α-reductase inhibitor, focal therapy, genome, marker, Prevention, risk, selenium, SNP, targeted | Leave a comment »
Posted on April 22, 2009 by Sitemaster
Today’s news reports deal with:
- A gene modification that may identify risk for prostate cancer
- Dietary intervention and prostate cancer management
- “Elastography” as a possible means to assess risk for prostate cancer
- Pain management in very late stage disease … READ MORE …
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: diet, elastography, gene, pain, predisposition, rs10993994, SNP | Leave a comment »
Posted on November 19, 2008 by Sitemaster
Today’s reports cover such items as:
- Disparities in cancer mortality between blacks and whites in the USA
- Body mass, body fat distribution, and risk for prostate cancer
- Risk for cancer in male carriers of BRCA mutations
- A five-SNP genetic marker set and prostate cancer risk
- Final results of the atrasentan trial in non-metastatic, HRPC patients
- Is a rising plasma PDGF level an indicator for docetaxel failure? … READ MORE …
Filed under: Drugs in development, Management, Prevention, Treatment | Tagged: atrasentan, BMI, BRCA mutation, disparity, docetaxel, fat distribution, genetic marker, PGDF, SNP | Leave a comment »