The first-line treatment of locally advanced prostate cancer (clinical stage T3)

Does radical prostatectomy (with or without external beam radiation therapy) improve prostate-cancer specific survival by comparison with primary radiation treatment and androgen deprivation therapy (ADT) among patients initially diagnosed with locally advanced (T3) prostate cancer? … READ MORE …

Salvage whole pelvic radiation after cancerous pelvic lymph nodes have been found

Is it still worthwhile to attempt salvage radiation therapy (SRT) after positive pelvic lymph nodes (PLN) have been pathologically detected (stage pN1)? … READ MORE …

Risk, prostate cancer, and being 70 to 80 years of age

So a relatively new article in Reviews in Urology caught your Sitemaster’s eye this morning — and worried him because it seemed to be communicating a conclusion of questionable accuracy, which we will explore below. And if we have misinterpreted the data provide in the paper, we are more than willing to be corrected. … READ MORE …

Test your knowledge on the diagnosis and staging of prostate cancer

Support group leaders and other prostate cancer educators may wish to test their knowledge on the diagnosis and staging of prostate cancer by reading through the set of 29 slides prepared by Kleynberg and Gross and just made available on the Medscape web site.

A real decrease in the use of RP in treatment of men with low-risk prostate cancer?

A new paper from clinical research teams at two French hospitals suggests that there has been a significant relative increase (from 2005 to 2010, at their institutions) in the percentage of men found to have pathological T3 as opposed to pathological T2 disease after radical prostatectomy (RP). … READ MORE …

The current state of focal therapy for localized prostate cancer

Many readers may be interested in two expert interviews on the OncologySTAT web site with Dr. Mark Emberton (a member of the Scientific Advisory Board of The “New “Prostate Cancer InfoLink). … READ MORE …

Long-term outcomes after RP as first-line therapy for men with cT3 disease at time of diagnosis

We have no data from randomized trials on the relative effectiveness of surgery compared to radiation therapy in the treatment of men initially diagnosed with clinical stage T3NxM0 prostate cancer. However, we do now have data from > 800 men treated with radical prostatectomy (RP) and followed for up to 23 years at the Mayo Clinic. … READ MORE …