Active surveillance in Oz: a situation report

An interesting article published a couple of week’s ago in the Medical Journal of Australia reports on “real world issues” related to the implementation of active surveillance (AS) in Oz. … READ MORE …

Low-dose abiraterone with food proves its worth in small Phase II trial

We have known for some time that taking abiraterone acetate (Zytiga) with food (as opposed to on an empty stomach) might well allow patients to be able to take significantly lower doses of this product and gain the same clinical benefit as is currently known to be beneficial from taking 1,000 mg/day when fasting. … READ MORE …

MRI-targeted biopsies: better than standard biopsies for at least some patients

A new article in this week’s New England Journal of Medicine has just reported the full results of the so-called PRECISION trial of MRI-targeted vs. standard biopsy techniques in the diagnosis of prostate cancer. … READ MORE …

Is MRI/TRUS fusion-guided prostate biopsy cost-efficient for all patients?

Slowly but perhaps inexorably we seem to be seeing increasing scientific and clinical justification for the argument that all men thought to be at risk for a diagnosis of prostate cancer should be given an MRI scan prior to any form of prostate biopsy. … READ MORE …

Changes to the standards for staging of prostate cancer

The most recent, 8th edition, of the American Joint Committee on Cancer (AJCC) Staging Manual has introduced some relatively minor modifications to the standards for staging of prostate cancer. … READ MORE …

The appropriate implementation of active surveillance as a management strategy

In addition to the prior article on management of low-risk prostate cancer in Canada comes another article that highlights the importance of what is called “active surveillance” (as opposed to what may actually be much less sophisticated forms of monitoring). … READ MORE …

Why we should care about standards of care?

“Standard of care” (SOC) is a legalistic term. As it applies to medicine, wh en a clinician follows an SOC, it means that he or she has proceeded with the reasonable caution that any minimally competent doctor would and should exercise in such circumstances. … READ MORE …