Record 10-year SBRT study among low-risk patients

Alan Katz has now published the study with the longest-running follow-up of any study of external beam radiation therapy for prostate cancer among low-risk patients, in this case using SBRT. … READ MORE …

After failure of first-line radiation, both kinds of salvage brachytherapy are equally effective

A group of researchers at Memorial Sloan-Kettering Cancer Center (MSKCC) reported in 2014 (see this link) on the outcomes of 42 patients with radio-recurrent prostate cancer treated with salvage high-dose-rate brachytherapy (sHDR-BT). The results were quite good — … READ MORE …

First US randomized clinical trial of oligometastasis-directed SBRT

In a recent commentary (see this link), we saw that some clinicians are making unsubstantiated claims of cancer control from treatment of oligometastases (less than 5 detected metastases). … READ MORE …

SBRT vs. standard IMRT as first-line radiation therapy for localized prostate cancer

Many readers may be interested in an article by Gina Kolata in today’s issue of The New York Times. It deals with the rising popularity of stereotactic body radiation therapy (SBRT) in the management of localized prostate cancer. … READ MORE …

SBRT vs. moderate hypofractionation: same or better quality of life?

In several randomized clinical trials of external beam treatment of primary prostate cancer, we have seen that moderately hypofractionated intensity-modulated radiation therapy (HypoIMRT), accomplished in 12 to 26 treatments or fractions, is no worse than conventionally fractionated IMRT treatment (in 40 to 44 fractions). … READ MORE …

Toxicity equal for SBRT and conventional external beam radiation (3D-CRT)

There has been some question as to whether the toxicity of delivering very high doses of external beam radiation per treatment (or fraction) in fewer fractions (called “extreme hypofractionation” or SBRT) would be high compared to conventional dose rates per fraction. … READ MORE …

5-Year SBRT trial: high cancer control, low toxicity

Data from a 5-year-long, multi-institutional trial, reported at the recent ASTRO meeting, showed that stereotactic body radiation therapy (SBRT) had high rates of cancer control and low toxicity. … READ MORE …