Risk stratification for radiation therapy

Risk stratification involves assigning patients to categories based on diagnostic risk factors. The goal is to identify those patients who are more or less likely to respond to specific therapies (or active surveillance). … READ MORE …

Risk stratification in diagnosis and management of prostate cancer

A new article by Vickers, Roobol, and Lilja, scheduled for publication in the January 2012 issue of the Annual Review of Medicine is likely to raise some eyebrows in the urology community. … READ MORE …

Treatment outcomes and the importance of Gleason pattern 5 in biopsy cores

D’Amico and colleagues have conducted a retrospective analysis of data from > 300 patients in an attempt to compare biochemical (PSA-based) outcomes of men with high-risk prostate cancer based on the presence or absence of any amount of Gleason pattern 5 cancer in their initial biopsy findings (as a primary, secondary, or tertiary pattern). The results emphasize the importance of the presence of tertiary Gleason pattern 5 tumor in patients with an overall Gleason score of 7. … READ MORE …