Are PCSP cells one of the keys to risk for prostate cancer metastasis?

A newly published paper in the journal called The Prostate has described a type of previously unidentified cell that may indicate the presence of a more aggressive subtype of prostate cancer. … READ MORE …

An aggressive, ETS-negative subtype of prostate cancer

A paper just published in Cancer Research suggests that a particular ETS-negative subtype of prostate cancer (ERGMAP3K7delCHD1del) is highly aggressive, and that coordinate loss of the MAP3K7 and CHD1 genes are potentially a unique driver of development of aggressive prostate cancer. … READ MORE …

Rare variants of adenocarcinoma of the prostate: a 25-year analysis of incidence and mortality

The vast majority of prostate cancers are adenocarcinomas of the prostate, i.e., cancers that start in the epithelial cells of the prostate gland. Most of these adenocarcinomas have a well-defined, “normal” cancer histology. However, there are five categories of rare adenocarcinoma, with differing levels of risk. … READ MORE …

Do SPOP mutations define a new molecular subtype of prostate cancer?

A Letter to the Editor just published in the journal Nature Genetics has suggested that that so-called SPOP mutations may be responsible for between 6 and 15 percent of the prostate cancers diagnosed in the USA each year. … READ MORE …