Outcomes of 55 men who had prophylactic RALPs for suspicion of unproven prostate cancer

Over the years, we have been asked several times whether there is a role for any type of  immediate treatment in men with a high level of concern for their risk of prostate cancer — despite a negative finding on prostate biopsy. … READ MORE …

The initial (10-year) results of the ProtecT trial: much as we might have expected?

So the majority of the readers of The “New” Prostate Cancer InfoLink will be well aware that we have never had data from a large, randomized clinical trial comparing the outcomes of the commonest first-line forms of management of men diagnosed with localized prostate cancer … READ MORE …

RALP vs. open surgery: “similar functional outcomes at 12 weeks”

Back in July we reported the initial publication on line of the results of a randomized Phase III trial by Yaxley et al. that compared the initial outcomes of open radical retropubic prostatectomy to robot-assisted laparoscopic prostatectomy (RALP). This paper has now been published by The Lancet along with two sets of editorial commentary. … READ MORE …

Alas, … the surgery vs. radiation therapy war continues …

In what certainly appears to be the largest and most thorough meta-analysis published to date, the authors conclude that surgery is a more effective first-line treatment for localized prostate cancer than radiation therapy. However, … READ MORE …

For very high-risk patients, EBRT + BT is superior to surgery or EBRT only

A retrospective analysis of oncological outcomes among modern-era patients with a Gleason score of 9 or 10 demonstrates a clear advantage to a combination of external beam radiation therapy (EBRT) with a brachytherapy (BT) boost to the prostate and short–term androgen deprivation therapy (ADT). … READ MORE …

RALP vs. ORP: data from a randomized Phase III clinical trial

A newly published paper in The Lancet has provided us with data from a randomized, Phase III, clinical trial of open radical retropubic prostatecomy (ORP) vs. robot-assisted laparoscopic prostatectomy (RALP) in the surgical treatment of localized prostate cancer. … READ MORE …

The end to WHAT controversy?

In an extraordinary editorial in the July issue of the Journal of Urology, Dr. Michael Koch of the University of Indiana School of Medicine makes the following statement: … READ MORE …