91 percent of Swedish men diagnosed with very low-risk prostate cancer now start on active surveillance

According to a new paper, just published in JAMA Oncology, the vast majority of Swedish men diagnosed with very low- and low-risk prostate cancer are now being initially managed on active surveillance. … READ MORE …

Does diagnosis/treatment for prostate cancer increase risk for colorectal cancer too?

A newly published study in the journal of Cancer Control has again suggested the possibility that men treated for prostate cancer may be at elevated risk for a secondary diagnosis of colorectal cancer by comparison with similar men never diagnosed with prostate cancer. … READ MORE …

Data from large Swedish study supports exercise after first-line therapy

According to a media release issued by the American Association for Cancer Research (AACR) new data from a large Swedish study show lower overall and prostate cancer-specific mortality in prostate cancer patients who exercise regularly. … READ MORE …

Surgery vs. radiation therapy in first-line treatment of prostate cancer: a travesty

Almost exactly a year ago, we commented unfavorably on a media release issued by the European Association for Urology (EAU). The media release referred to a presentation made by Sooriakumaran et al. at the annual meeting of the EAU in 2013. … READ MORE …

Recent utilization of active surveillance to defer treatment in Sweden

Although many US urologists and radiation oncologists consider that active surveillance is a highly appropriate form of management for low and very low-risk forms of prostate cancer, the actual use of active surveillance in clinical practice here in the USA is still limited … so it is interesting to see recent data from Sweden on this topic. … READ MORE …

A 17 percent potency rate post-surgery in one Swedish study

According to another media release issued on Sunday by the European Association of Urology, only 17 percent of a large cohort of Swedish men with prostate cancer who were potent prior to surgery were still potent 18 months post-surgery (whether they had nerve-sparing or non-nerve-sparing surgery). … READ MORE …

Badly judged and biased political spin from the European Association for Urology

According to a media release issued by the European Association of Urology on Saturday, just prior to the opening of their annual meeting in Milan, Italy, “Surgery is superior to radiotherapy in men with localized [prostate cancer].” This headline is not even justifiable based on the content of the media release. … READ MORE …

Final report of the 30-year-long Swedish study of watchful waiting in management of localized prostate cancer

Since 1977 a group of Swedish researchers has followed a prospectively evaluated, population-based cohort of 223 consecutive patients, all diagnosed clinically with localized prostate cancer, who received no treatment other than observation (“watchful waiting”) until symptomatic progression and androgen deprivation therapy (ADT) became necessary. … READ MORE …

Use of PSA testing increases by 130 percent in Sweden over 9 years

A new study in European Urology has provided information about expansion of use of the PSA test in Sweden — by some 130 percent — between 2003 and 2011. This despite the fact that (rightly or wrongly) mass population-based screening for prostate cancer is not recommended in Sweden. … READ MORE …

Psychiatric treatment among Swedish men with prostate cancer

A new paper in the European Journal of Cancer suggests that men with prostate cancer are at increased risk for depression, for post-traumatic stress disorder, and for use of antidepressant drugs compared to age-matched controls. … READ MORE …

Prostate cancer-specific mortality after non-curative treatment of locally advanced disease

A new analysis of information from the Swedish national prostate cancer registry database and the Swedish cause of death register has confirmed the importance of aggressive, curative treatment of men with locally advanced prostate cancer. … READ MORE …

Risk for prostate cancer-specific and other forms of mortality at 15 years of follow-up

An interesting study presented at the European Association of Urology meeting in Vienna recently documented risk for prostate cancer-specific and other forms of mortality within 15 years of diagnosis for Swedish men initially diagnosed with low- and intermediate-risk prostate cancer. … READ MORE …

The Norrkoping prostate cancer screening trial — with 20-year follow-up

A new report just published as an open access, full-text article at BMJ.com is going to further confuse the issue of whether mass, population-based screening for prostate cancer is or isn’t a good idea. … READ MORE …

Comorbidity, treatment, and mortality among Swedish prostate cancer patients

A clear appreciation of the associations between life expectancy, comorbid conditions (e.g., diabetes, obesity, cardiovascular disorders), and mortality is critically important to treatment decisions for all patients with prostate cancer, but most especially the newly diagnosed, low-risk patient. … READ MORE …